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Dr. Nickolai Dulin studies the signaling mechanisms of myofibroblast differentiation as related to the pathogenesis of pulmonary fibrosis. This includes the signaling induced by TGF-beta and by G protein coupled receptors, control of cell signaling by actin and microtubule sytoskeleton, activation of mechanosensitive transcription factors and identification of their target genes, and control of these processes through protein phosphorylation. His studies using cultured human lung fibroblasts and animal models of pulmonary fibrosis aim to identify new signaling molecules that could be targeted for potential treatment of this disease.
Dr. Nickolai Dulin studies the signaling mechanisms of myofibroblast differentiation as related to the pathogenesis of pulmonary fibrosis. This includes the signaling induced by TGF-beta and by G protein coupled receptors, control of cell signaling by actin and microtubule sytoskeleton, activation of mechanosensitive transcription factors and identification of their target genes, and control of these processes through protein phosphorylation. His studies using cultured human lung fibroblasts and animal models of pulmonary fibrosis aim to identify new signaling molecules that could be targeted for potential treatment of this disease.
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论文共 104 篇作者统计合作学者相似作者
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Eleanor B Reed, Albert Sitikov, Robert B Hamanaka,Rengul Cetin-Atalay, Gokhan M Mutlu, Alexander A. Mongin,Nickolai O Dulin
crossref(2024)
International Journal of Molecular Sciencesno. 4 (2023): 3930-3930
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Eleanor B. Reed, Shaina Orbeta, Bernadette A. Miao,Albert Sitikov, Bohao Chen,Irena Levitan, Julian Solway,Gökhan M. Mutlu, Yun Fang, Alexander A. Mongin,Nickolai O. Dulin
biorxiv(2023)
Shehab Eid, Thomas Zerbes,Declan Williams,Xinzhu Wang, Chris Sackmann, Sammy Meier,Nickolai O Dulin,Pavel Nagorny,Gerold Schmitt-Ulms
FRONTIERS IN PHYSIOLOGY (2020): 590262-590262
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