Nicholas J Davies

Clonal evolution in cancer and leukaemia contributes to the heterogeneity of the disease. This hetereogeneity is believed to play a critical role in how the disease progresses and its response to therapy. Currently my research is interested in developing novel ways to track subclones within leukaemia to assess how different treatments affect clonality. This work entails the use of multi-colour FISH, SNP arrays and next generation sequencing alongside a novel xenograft model of CLL.