Dr Nick Brooks is a Reader in the Department of Chemistry, Imperial College London.
My group's research focuses on the effect of high pressure on the structure and micromechanics of biological membranes, and dynamic structural changes in membrane based systems. Coupled to these research aims, we have a strong interest in advanced instrumentation and technique development.
I am a leading member of the Membrane Biophysics Platform which is working at the forefront of the emerging field of molecular membrane engineering to design and construct new biologically-inspired materials and devices. We aim to revolutionise the design and fabrication of smart, soft materials and catalyse a paradigm shift in areas such as nanomedicine, bioelectronics, biological computing devices and synthetic organelles.
Much of our work is underpinned by development of new instrumentation (particularly high pressure platforms) to access experiments that were not previously possible. We have developed world-class systems for high pressure and pressure-jump microscopy and this has led to collaborations across the UK, Europe and USA. Having established an internationally leading pressure-jump facility for small angle X-ray diffraction at Diamond Light Source, we have been involved in the development of further related facilities at both Diamond and ESRF as well as a range of synchrotron based sample environments for probing structural changes in soft materials in response to triggers including solvent environment and electric field.