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Transposons, also called mobile DNA elements or ‘jumping genes’, are abundant in almost all living things. In humans, transposons occupy about 50% of the DNA and are still able to mobilize in the human genome. Recent studies show that transposons can affect embryonic development, neurogenesis, and are related with over 100 different types of diseases. However, the detailed mechanism and functions of transposons remain largely unexplored. Through ‘wet lab’ and ‘dry lab’ techniques, we will study the mechanism of transposon regulation and the roles of transposons in development and disease.
Transposons, also called mobile DNA elements or ‘jumping genes’, are abundant in almost all living things. In humans, transposons occupy about 50% of the DNA and are still able to mobilize in the human genome. Recent studies show that transposons can affect embryonic development, neurogenesis, and are related with over 100 different types of diseases. However, the detailed mechanism and functions of transposons remain largely unexplored. Through ‘wet lab’ and ‘dry lab’ techniques, we will study the mechanism of transposon regulation and the roles of transposons in development and disease.
Research Interests
Papers共 29 篇Author StatisticsCo-AuthorSimilar Experts
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Dan Wang,Kun Yan, Hongxing Yu, Haocheng Li,Wei Zhou,Yaqiang Hong,Shuning Guo,Yi Wang, Cheng Xu,Changcun Pan,Yujie Tang,Nian Liu,
CANCER RESEARCHno. 4 (2024): 598-615
Xiufeng Li,Luyao Bie,Yang Wang,Yaqiang Hong, Ziqiang Zhou, Yiming Fan, Xiaohan Yan, Yibing Tao,Chunyi Huang, Yongyan Zhang, Xueyan Sun,John Xiao He Li,
Nature geneticsno. 7 (2024): 1494-1502
Xiufeng Li,Luyao Bie,Yang Wang,Yaqiang Hong, Ziqiang Zhou, Yiming Fan, Xiaohan Yan, Yibing Tao,Chunyi Huang, Yongyan Zhang, Xueyan Sun,John Xiao He Li,
Nature genetics (2024)
Dan Wang,Kun Yan, Hongxing Yu, Haocheng Li,Wei Zhou,Yaqiang Hong,Shuning Guo,Yi Wang, Cheng Xu,Changcun Pan,Yujie Tang,Nian Liu,
Cancer researchno. 4 (2024): 598-615
Yaqiang Hong,Luyao Bie, Tao Zhang, Xiaohan Yan, Guangpu Jin,Zhuo Chen,Yang Wang, Xiufeng Li,Gaofeng Pei, Yongyan Zhang,Yantao Hong,Liang Gong,
Cell stem cellno. 6 (2022): 948-961.e6
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