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个人简介
My group is focused on life-threatening fungal diseases. These infections pose difficulties in diagnosis, there are no vaccines for fungal disease, and treatment options are limited.
Fungal cells are surrounded by wall that is composed of signature molecules that are not represented at all in the human body. The cell wall is therefore the target which immune system uses to recognise the presence of a fungal invader and it is also an excellent target to aim the design of antifungal drugs.
For these reasons my group’s speciality is to understand how the fungal cell wall is made, how it is detected by our immune system and how we might kill fungi by blocking cell wall assembly. This research is therefore informing the design of new generations of antifungal drugs and diagnostic tests.
Fungal cells are surrounded by wall that is composed of signature molecules that are not represented at all in the human body. The cell wall is therefore the target which immune system uses to recognise the presence of a fungal invader and it is also an excellent target to aim the design of antifungal drugs.
For these reasons my group’s speciality is to understand how the fungal cell wall is made, how it is detected by our immune system and how we might kill fungi by blocking cell wall assembly. This research is therefore informing the design of new generations of antifungal drugs and diagnostic tests.
研究兴趣
论文共 510 篇作者统计合作学者相似作者
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The Journal of infectious diseases (2024)
The Cell Surface (2024): 100128-100128
Leandro Honorato, Jhon J Artunduaga Bonilla,Alessandro F Valdez,Susana Frases,Glauber Ribeiro de Sousa Araújo, Albaniza Liuane Ribeiro do Nascimento Sabino, Natalia Martins da Silva, Larissa Ribeiro,Marina da Silva Ferreira, Julio Kornetz, Marcio L Rodrigues,Iain Cunningham,
mSpherepp.e0046724-e0046724, (2024)
biorxiv(2024)
Gabriela M. Avelar,Arnab Pradhan,Qinxi Ma,Emer Hickey,Ian Leaves,Corin Liddle, Alejandra V. Rodriguez Rondon,Ann-Kristin Kaune,Sophie Shaw,Corinne Maufrais,Natacha Sertour,Judith M. Bain,
mBiono. 2 (2024): e0189823-e0189823
Stella Wolfgruber, Sarah Sedik,Lena Klingspor, Annamaria Tortorano,Neil A. R. Gow,Katrien Lagrou, Jean-Pierre Gangneux,Johan Maertens,Jacques F. Meis,Cornelia Lass-Flörl, Sevtap Arikan-Akdagli,Oliver A. Cornely,
Mycopathologiano. 4 (2024): 70-70
EClinicalMedicine (2024): 102616
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The Cell Surface (2024): 100119-100119
JOURNAL OF INFECTIOUS DISEASES (2024)
NATURE REVIEWS MICROBIOLOGYpp.1-18, (2024)
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作者统计
#Papers: 509
#Citation: 39084
H-Index: 100
G-Index: 188
Sociability: 7
Diversity: 4
Activity: 113
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