基本信息
浏览量:2
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
My research focuses on the molecular mechanisms of learning and memory; the internal and external factors that can lead to changes in memory; and the role of memory dysregulation in psychiatric and neurological disorders including post-traumatic stress disorder, and post-operative cognitive decline. We are particularly intruigued by questions such as “Why do many patients develop post-traumatic stress disorder after heart attack?” and “What causes cognitive and memory decline after surgery?” and “How do normal memories for trauma become pathological in post-traumatic stress disorder?” and “Why are women so much more susceptible to these than males?”
Therefore, we focus on mechanisms by which neuroimmune signaling and stress lead to enhancements or impairments in long term memory formation; in the role of memory reconsolidation after retrieval in maladaptive memory; and the similarities and differences in how males and females form and modulate memory.
To study these questions, we integrate behavioral measures of memory in mice - including fear conditioning and appetitive pavlovian conditioning; models of illness including surgical induction of myocardial infarction (a model of heart attack); and protein biochemistry to measure changes in cytokines, signal transduction, and transcription.
Therefore, we focus on mechanisms by which neuroimmune signaling and stress lead to enhancements or impairments in long term memory formation; in the role of memory reconsolidation after retrieval in maladaptive memory; and the similarities and differences in how males and females form and modulate memory.
To study these questions, we integrate behavioral measures of memory in mice - including fear conditioning and appetitive pavlovian conditioning; models of illness including surgical induction of myocardial infarction (a model of heart attack); and protein biochemistry to measure changes in cytokines, signal transduction, and transcription.
研究兴趣
论文共 63 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Kristen M. Schuh,Jabir Ahmed,Esther Kwak, Cecilia X. Xu, Tronjay T. Davis, Chloe B. Aronoff,Natalie C. Tronson
biorxiv(2023)
FRONTIERS IN NEUROENDOCRINOLOGY (2023): 101063-101063
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2021)
加载更多
作者统计
#Papers: 63
#Citation: 3177
H-Index: 27
G-Index: 43
Sociability: 5
Diversity: 3
Activity: 26
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn