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A crucial aspect of many of human diseases such as cancer, inflammatory diseases, and age-related macular degeneration is the formation of new blood vessels known as angiogenesis. Our laboratory is studying molecular mechanisms of angiogenesis and its application to human diseases, in particular its role in cancer and ocular diseases. An understanding of how angiogenic signals are being instigated and fine-tuned will help in the design of more effective anti-angiogenesis therapies. More recently, our laboratory has identified a number of novel and uncharacterized transmembrane proteins. The course of our research changed radically when we discovered that these cell surface receptors act as cell adhesion molecule and play critical role in endothelial and epithelial biology. A brief description of the current projects is outlined below
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Molecular metabolism (2023): 101744-101744
The American Journal of Pathologyno. 1 (2021): 157-167
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