He participates in some observational studies and registries regarding cancer associated thrombosis (CAT), neuroendocrine tumours, pancreatic cancer, anti-EGFR treatment in colorectal cancer, liquid biopsies in non-small cell lung cancer, male breast cancer, kidney cancer, BRCA mutations in ovarian cancer and lynch syndrome. Additionally, he is a member of multidisciplinary teams for neuroendocrine tumours and adrenal tumours in Athens.
Dr Tsoukalas has published interesting papers regarding mainly biomarkers (RCAS1, Ephrins, HuR, COX2, HDAC, FAK/SRC, FXR, EMT, etc) in different tumour types, useful reviews regarding bisphosphonates, quality assurance, dermatomyositis and cancer, pancreatic carcinoids, abnormal DNA methylation and a meta-analysis regarding the predictive value of KRAS in colorectal cancer. He has a few comprehensive publications regarding some hereditary aspects of cancers such as breast and gastric cancer. Dr Tsoukalas has written chapters in oncology books and he is a reviewer for different medical journals.