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Research Topics
Research in the Cell Biology Section spans the basic sciences, clinical trials, and epidemiology. Bench work involves methods of cell and molecular biology, immunology, and virology. Blood cell production in healthy individuals and especially in patients with bone marrow failure is the main theme. Advanced techniques most recently include single cell RNAseq, CRISPR-Cas9 gene editing, multicolored bar coded flow cytometry, and SomaLogic deep proteomics. Use of patient samples is encouraged, as the Hematology Branch clinic for patients with aplastic anemia, paroxysmal nocturnal hemoglobinuria (PNH), myelodysplastic syndromes (MDS), large granular lymphocytosis (LGL), and constitutional marrow failure is one of the largest in the world. Results in the laboratory have had real impact on the care of patients with these life-threatening illnesses, and access to patient samples over time and with therapeutic perturbation makes the laboratory strategies both innovative and concrete.
研究兴趣
论文共 1047 篇作者统计合作学者相似作者
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Ashvind Prabahran, Jibran Durrani, Juan Coelho-Da Silva,Ruba Shalhoub,Jennifer Lotter,Olga Rios,David S Ritchie, Colin O Wu,Bhavisha A Patel,Neal S Young,Emma M Groarke
British journal of haematology (2024)
Saravanan Ganesan,Rebecca M. Murray,Jesus Sotelo, Elliot O. Eton, Kouhei Takashima,Theo Botella, Kai Beattie, Alyssa C. Indart, Nada Chraiki, Carolyne Croizier,Franco Izzo,Catherine Potenski,
biorxiv(2024)
BRITISH JOURNAL OF HAEMATOLOGY (2024)
Haematologicano. 5 (2024): 1603-1607
British journal of haematologyno. 5 (2024): 2121-2124
Rachel Sparks,Nicholas Rachmaninoff,William W Lau, Dylan C Hirsch,Neha Bansal,Andrew J Martins, Jinguo Chen,Candace C Liu,Foo Cheung,Laura E Failla,Angelique Biancotto,Giovanna Fantoni,
Nature medicinepp.1-12, (2024)
Haematologicano. 6 (2024): 1792-1799
João Paulo L. Silva,Flávia S. Donaires,Fernanda Gutierrez-Rodrigues,Davi J. Martins,Vinicius S. Carvalho,Barbara A. Santana,Renato L. G. Cunha,Sachiko Kajigaya, Carlos F. M. Menck,Neal S. Young,Eigil Kjeldsen,Rodrigo T. Calado
Molecular Biology Reportsno. 1 (2024): 1-13
ANNALS OF THE RHEUMATIC DISEASESno. 4 (2024): 508-517
Isabella J Tan,Marcela A Ferrada,Serene Ahmad,Alice Fike,Kaitlin A Quinn,Emma M Groarke,David B Beck, Jill Allbritton, Leslie Castelo-Soccio,Neal S Young,Bhavisha A Patel,Peter C Grayson,
JAMA dermatology (2024)
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