Since 1993 Dr Normanno’s area of research has been the study of the role of growth factors and receptors of the EGF family in the pathogenesis of solid tumours; the use of antisense oligonucleotides and inhibitors of receptors in experimental models of molecular therapy of carcinomas; identification of markers of response or resistance to anti-EGFR agents.

Dr Normanno is a member of the European Society for Medical Oncology (ESMO), the American Association for Cancer Research (AACR), the Italian Association of Medical Oncology (AIOM), and the Italian Cancer Society (SIC). He is from 2018 President of the International Quality Network for Pathology (IQN Path) and President Elect of the Italian Cancer Society (SIC).