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The goals of the research conducted in our laboratory are to discover prognostic markers and to characterize their biological roles in the oncogenic processes leading to the development of prostate cancer. Our laboratory uses a combination of biological approaches including genomic, computational/bioinformatic, evolutionary, molecular, cellular and developmental methods for an integrated approach to prostate cancer research, concentrated on identifying the underlying cause of observed disparities in prostate cancer incidence rates between men with different genetic ancestries now living in the United States. It is my hope that the elimination of prostate cancer incidence and mortality rate disparities in African American Men can be accomplished with population stratification using risk prediction alleles identified by mapping by admixture linkage disequilibrium. These alleles may identify causal mechanisms of cancer initiation and progression that can be leveraged to develop effective strategies for prevention and management of prostate cancer in all men.
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Translational oncology (2023): 101707-101707
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTIONno. 12 (2023)
Cancer Epidemiology, Biomarkers & Preventionno. 1_Supplement (2023): C023-C023
Xin Li,Yanhua Chen,Lijuan Bai, Rui Zhao,Yifei Wu,Zhong-Ru Xie, Jason M Wu,Nathan J Bowen,Alira Danaher,Nicholas Cook,Dehong Li,Min Qui,
Taaliah Campbell,Ohuod Hawsawi,Veronica Henderson,Precious Dike, Bor-Jang Hwang,Yusuf Liadi,ElShaddai Z. White,Jin Zou,GuangDi Wang,Qiang Zhang,Nathan Bowen, Derrick Scott,
Cancer Epidemiology, Biomarkers & Preventionno. 1_Supplement (2023): C044-C044
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTIONno. 1 (2023): 238-238
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