基本信息
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个人简介
PhD, Doc. Sci. (Biology)
CURRENT POSITION HELD
Senior researcher - 2001 – present
RE. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology,
National Academy of Sciences of Ukraine, Vasylkivska, 45, 03022 Kyiv, Ukraine
• Research supervisor or responsible executor of more than 30 research projects and both grants commissioned by the Ukrainian government and international pharmaceutical companies on biotechnology, cell culture, drug screening, and active pharmaceutical ingredient studies
• Author on more than 160 basic science oncology and applied clinical oncology publications, including studies on novel drug screening, oncology drug testing and oncology diagnostics test development (Oncotarget, Cytokine, Drug Delivery, BMC Pharmacology and Toxicology, Analytical Oncology, International Journal of Oncology, Cancer Research Journal, Experimental Oncology, Oncology, Cell and Organ Transplantology, Cytology, Biopolymers and Cell, and Polish Journal of Veterinary Science)
EDUCATION AND TRAINING
RE. KAVETSKY INSTITUTE OF EXPERIMENTAL PATHOLOGY, ONCOLOGY AND RADIOBIOLOGY, NAS OF UKRAINE, Kyiv, Ukraine
Doctor of sciences in biology, with an oncology research specialization 2016 – 2020
• Thesis: “Factors of the epithelial-mesenchymal transition of cells in the tumor process and sensitivity to medication therapy”
RE. KAVETSKY INSTITUTE OF EXPERIMENTAL PATHOLOGY, ONCOLOGY AND RADIOBIOLOGY, NAS OF UKRAINE, Kyiv, Ukraine
PhD in biology, with an oncology research specialization 2004 – 2009
• Thesis: “Modification of in vitro biological properties of human lung cancer cells by interferon-alpha”
TARAS SHEVCHENKO KYIV NATIONAL UNIVERSITY, BIOLOGY,
MICROBIOLOGY AND IMMUNOLOGY DEPARTMENT, Kyiv, Ukraine
Master’s in microbiology and virology with an immunology specialization 1998 – 2004
• Theoretical and practical training in biochemistry, molecular biology, biotechnology, genetics, immunology, microbiology, virology, and cell biology
TRAINING AND SKILLS
• Laboratory techniques: Cell culture, molecular oncology, cancer stem cells, epithelial-mesenchymal transition, cytokines, in vitro and in vivo cellular models, biological therapies, translational medicine, personalized medicine
o Cell culture: Mammalian and human cell culture lines including tumor and non-cancerous cell culture, cryopreservation and reconstitution, primary cell culture, co-cultivation, transfection, transduction; cell adhesion and invasion assays, isolation and work with blood and bone marrow cells, study of cytokines, scratch assay, cell proliferation and viability assay, drug testing including anti-tumor, anti-inflammatory assays
o Molecular methods: ELISA, immunocytochemistry, fluorescence microscopy, molecular cloning
o Animal studies: Drug administration including enteral, oral, intragastric, parenteral, intramuscular, intravenous, animal behaviour tests, in vivo study of anticancer drugs in experimental animal models.
o Other techniques: Study of individual antitumor sensitivity to drugs in vitro, evaluation and characterization of pathological conditions in vitro and in vivo including inflammation, psoriasis, fibrosis, steatosis, cytokine storm and others.
• Scientific writing and presentations: Grant applications, creation of scientific and popular science lectures, presentations, preparation of protocols, SOPs and other documents for laboratory accreditation and certification. Formulating preclinical study plans, documents according to GLP standards, maintaining and consulting, scientific support of protocols and reports of preclinical studies of drugs according to GLP standards. Reviewing articles and project, writing applications and grant projects, registration and submission of grants.
SELECT SCIENTIFIC ORAL AND POSTER PRESENTATIONS
• “Making it Personal: Cancer Precision Medicine”, Amsterdam, Netherlands, 2017.
• International VACTRAIN/ 3rd Swedish-Ukrainian conference, Stockholm, Sweden, 2017.
• International Congress of the European Federation for Colorectal Cancer (EFR), Vienna, Austria, 2013.
• BRIC 10-year Anniversary Symposium on Cancer Biology, Copenhagen, Denmark, 2013.
• 9 th International Symposium on Minimal Residual Cancer, Paris, France, 2013.
• The 2nd Ukrainian-Swedish workshop “Translational Oncology: Old and New Paradigms”, Kyiv, Ukraine, 2013.
• 10th CIMT Annual Meeting «Towards Next-Generation Cancer Immunotherapy», Mainz, Germany, 2012.
• International conference “Tumor and host: novel aspects of old problem”, 2010, Kyiv, Ukraine.
研究兴趣
论文共 10 篇作者统计合作学者相似作者
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时间
引用量
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期刊级别
合作者
合作机构
Cell and Organ Transplantologyno. 2 (2021)
EUREKA: Life Sciencespp.12-22, (2020)
Scientific Works of National University of Food Technologiesno. 6 (2020): 56-67
V F Chekhun,N Y Lukianova,S V Chekhun,N O Bezdieniezhnykh, T V Zadvorniy,T V Borikun, L Z Polishchuk, O М Klyusov
作者统计
合作学者
合作机构
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