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Bio
My current role is as Professor of Biomedical Science and University Theme lead for Biomedical and Clinical Science Research at the University of Derby. In this role, I am responsible for leading and developing research centres across the College of Science and Engineering and the College of Health, Psychology and Social Care. The theme vision is to promote a research culture that works across boundaries, establishing interdisciplinary teams to focus on delivering translational research, which informs curriculum and student experience. I also lead an active research team, where our research focus is on 'Redox Biochemistry, Aging, Neurodegeneration and Biomarker development'
My previous posts were at the University of Brighton and the University of the West of England (from lecturer through to Professor in Biomedical Science). In these roles, I led research teams for 18 years in research areas that focussed on redox signalling in Alzheimer’s disease and Breast Cancer. I had the pleasure of supervising over 100 student research projects at undergraduate and MSc level. I am passionate about teaching with over 18 years’ experience in the fields of Biochemistry, Nutrition and Clinical Biochemistry. I recently obtained my Senior Fellowship in Teaching and Learning, which reflected on my interest is creating the optimal learning environment across space and place, together with curriculum and programme design.
These posts were underpinned by my 5-year Research Fellowship at Wake Forest University Medical Centre, NC, USA. Here, I had the pleasure of working with the most inspiring biochemists in a vibrant research environment, which fostered collaboration and blue skies research ambition. Prior to my Research Fellowship in the US, I graduated with a PhD in Clinical Biochemistry from the University of Galway Ireland, and where I obtained a first-class honours degree in Biochemistry (Minor Microbiology). I also have a Diploma in Food Science and Biotechnology from the Munster Technological University (Cork), Ireland.
My research aims to understand how changes in the redox environment can influence the structure/function relationships of proteins under both normal and pathophysiological conditions, in particular proteins with reactive thiol groups. Currently, I have several active research areas:
• Investigating the role of the branched chain aminotransferase (BCAT) proteins in regulating autophagy, a key contributor to the pathogenesis of neurodegenerative disorders such as Alzheimer's disease (AD).
• Understanding the link between diabetes and Alzheimer’s disease.
• The role of the BCAT protein in the pathology of Breast Cancer.
• Development of metabolic maps to ascertain key redox partners that regulate brain glutamate metabolism and protein folding and how this can change with age and age-related conditions.
• Development of biomarker profiles, which are designed to distinguish between patients with Mild Cognitive Impairment (MCI) and AD, a much-needed tool in this research area.
Research Interests
Papers共 58 篇Author StatisticsCo-AuthorSimilar Experts
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In Vitro Cellular & Developmental Biology - Animalpp.1-10, (2024)
James Hillier, Gemma J Allcott, Laura A Guest,Wayne Heaselgrave,Alex Tonks,Myra E Conway,Amy L Cherry,Steven J Coles
Encyclopedia of Biological Chemistry IIIpp.10-21, (2021)
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Mai Ahmed Shafei,Thomas Forshaw, Jasmine Davis,Arwa Flemban,David Qualtrough,Sarah Dean,Claire Perks,Ming Dong, Robert Newman,Myra Elizabeth Conway
Mai Ahmed Shafei,Arwa Flemban, Carl Daly, Paul Kendrick,Paul White,Sarah Dean,David Qualtrough,Myra E. Conway
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Author Statistics
#Papers: 52
#Citation: 1584
H-Index: 26
G-Index: 39
Sociability: 5
Diversity: 0
Activity: 1
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