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Bio
Debabrata (Dev) Mukhopadhyay, Ph.D., has a broad background in tumor microenvironment with training and expertise in angiogenesis, cancer, cardiovascular diseases and diabetes. Dr. Mukhopadhyay and his team are using pancreatic and renal cancer disease models to examine how tumors develop and particularly how they induce the angiogenic response that is essential for their survival.
Vascular permeability factor (VPF), also known as vascular endothelial growth factor (VEGF), has been implicated in the new vessel development found in most tumors. Although the mechanism of these complex processes remains unclear, Dr. Mukhopadhyay and his team are investigating the importance of VPF-VEGF as well as its signaling pathways to elucidate the mechanisms by which VPF-VEGF function in a variety of tumor models.
Moreover, Dr. Mukhopadhyay and his team are stuying the role of other angiogenic-related factors in tumor angiogenesis and metastasis, such as vascular endothelial growth factor C (VEGFC), vascular endothelial growth factor D (VEGFD) and phosphatidylinositol glycan anchor biosynthesis class F protein (PIGF).
Additional research interests include stellate cell biology, new drug delivery systems and nanotechnology, and incorporating the use gold nanoparticles and other bioconjugates as messengers to deliver reagents capable of manipulating the angiogenic response in vivo.
Vascular permeability factor (VPF), also known as vascular endothelial growth factor (VEGF), has been implicated in the new vessel development found in most tumors. Although the mechanism of these complex processes remains unclear, Dr. Mukhopadhyay and his team are investigating the importance of VPF-VEGF as well as its signaling pathways to elucidate the mechanisms by which VPF-VEGF function in a variety of tumor models.
Moreover, Dr. Mukhopadhyay and his team are stuying the role of other angiogenic-related factors in tumor angiogenesis and metastasis, such as vascular endothelial growth factor C (VEGFC), vascular endothelial growth factor D (VEGFD) and phosphatidylinositol glycan anchor biosynthesis class F protein (PIGF).
Additional research interests include stellate cell biology, new drug delivery systems and nanotechnology, and incorporating the use gold nanoparticles and other bioconjugates as messengers to deliver reagents capable of manipulating the angiogenic response in vivo.
Research Interests
Papers共 274 篇Author StatisticsCo-AuthorSimilar Experts
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Sleep Medicine (2024): 518-525
Shuman Zhang, Duo Yun, Hao Yang, Markus Eckstein, Gihan Daw Elbait, Yaxing Zhou, Yanxi Lu,Hai Yang, Jinping Zhang,Isabella Dörflein,Nathalie Britzen-Laurent,Susanne Pfeffer,
Cell Death Discoveryno. 1 (2024): 124-124
Gavin R. Schnitzler,Helen Kang, Shi Fang,Ramcharan S. Angom,Vivian S. Lee-Kim,X. Rosa Ma,Ronghao Zhou,Tony Zeng,Katherine Guo, Martin S. Taylor,Shamsudheen K. Vellarikkal,Aurelie E. Barry,
Natureno. 8000 (2024): 799-807
Shuman Zhang, Duo Yun, Hao Yang, Markus Eckstein, Gihan Daw Elbait, Yaxing Zhou, Yanxi Lu,Hai Yang, Jinping Zhang, Isabella Doerflein,Nathalie Britzen-Laurent,Susanne Pfeffer,
CELL DEATH DISCOVERYno. 1 (2024)
Shuman Zhang, Duo Yun, Hao Yang, Markus Eckstein, Gihan Daw Elbait, Yaxing Zhou, Yanxi Lu,Hai Yang, Jinping Zhang,Isabella Dörflein,Nathalie Britzen-Laurent,Susanne Pfeffer,
Cell death discoveryno. 1 (2024): 124-124
Emmanuel M. Gabriel,Deborah Bahr, Hari Krishnareddy Rachamala, Vijay S. Madamsetty,Barath Shreeder,Sanjay Bagaria, Amber L. Escobedo,Joel M. Reid,Debabrata Mukhopadhyay
ACS BIOMATERIALS SCIENCE & ENGINEERING (2024)
Vinitha N. Ragavan,Pramod C. Nair,Natalia Jarzebska,Ramcharan Singh Angom,Luana Ruta,Elisa Bianconi,Silvia Grottelli, Natalia D. Tararova, Daniel Ryazanskiy,Steven R. Lentz,Sara Tommasi,Jens Martens-Lobenhoffer,
Nature Communicationsno. 1 (2023): 1-16
Arteriosclerosis, thrombosis, and vascular biologyno. 10 (2023): 1921-1934
Hari K Rachamala,Vijay S Madamsetty, Ramcharan S Angom, Naga M Nakka,Shamit Kumar Dutta,Enfeng Wang,Debabrata Mukhopadhyay,Krishnendu Pal
Research squareno. 1 (2023): 159-159
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