Set up my independent laboratory programme in glomerular cell biology in Bristol, as well as holding a post as a consultant paediatric nephrologist since 1999, with an international reputation in management of nephrotic syndromes.
I was the originator of the UK Renal Rare Disease Registry (RaDaR), and am currently leading the UK nephrotic syndrome study (NephroS), as well as a major industry-academic collaboration termed NURTuRE (National Unified Renal Translational Research Enterprise). I am PI on several MRC projects, including Stratified Medicine, laboratory project grants and a Global Challenges programme.
My gene therapy program commenced in 2014, and is focused on targeting the podocyte in order to radically change the treatment of kidney diseases.