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Bio
-Mohamed S. Nafie (Ph.D.), Lecturer of Biochemistry and Drug Design, Chemistry Department, Faculty of Science, Suez Canal University, Ismailia (P.O. 41522), Egypt. I have obtained my Ph.D. (Biochemistry& Biological Chemistry) from Suez Canal University & Università di Pisa (Italy).
Email: mohamed_nafie@science.suez.edu.eg
- My research area is to design novel target-oriented chemotherapeutic anti-cancer agents using the Computer-Aided Drug Design (CADD), Biochemical, and Molecular biology assays.
- My experience in
- Proteomic characterization of venomous animals (scorpions).
- Biologically guided identification and fractionation of natural products or medicinal plants with structure identification using GC-LC-MS and HPLC tools.
- Biochemical and molecular analysis of the activity of novel chemotherapeutic anti-cancer agents using standard tissue culture techniques (MTT, MTS, and SRB assays), flow cytometry, SDS-PAGE, Western blot assays, and RT-PCR analysis for apoptotic genes as a mechanism of action.
- Interpretation of spectroscopic techniques (IR, Mass, NMR, and UV)
- Good knowledge of computational and medicinal chemistry studies, including molecular modeling (visualization) using Pymol, Chimera, and Maestro, Molecular Docking using MOE, Dock6, rDock, GlamDock, AutoDock4, AutoDockVina, Gold (ASP, PLP, Chemscore, and Goldscore), Fred and Plants. Moreover, Virtual Screening and Quantitative Structure-Activity Relationship (QSAR) using FLAP software.
Research Interests
Papers共 125 篇Author StatisticsCo-AuthorSimilar Experts
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METABOLITESno. 1 (2024): 27
JOURNAL OF MOLECULAR STRUCTURE (2024): 137906
Mahrous A. Ibrahim, Ayman Fathi Elsharawy, Waleed E. Abo Baraka,Athar M. Khalifa,Metwally E Abdalla,Mohamed S. Nafie,Shaimaa A. Shehata, Gamal Abdelrahman Bakhaat
Egyptian Journal of Forensic Sciencesno. 1 (2024): 1-15
Archives of Microbiologyno. 6 (2024): 1-27
METABOLITESno. 1 (2024)
Donia El Sayed,Samir M. El Rayes, Hamdy A. Soliman, Imad Eddin Albalaa,Mansour S. Alturki, Abdulaziz Hassan Al Khzem, Mohammed Abdullah Alsharif,Mohamed S. Nafie
Biomass Conversion and Biorefinerypp.1-14, (2024)
Journal of biochemical and molecular toxicologyno. 4 (2024): e23690-e23690
Archives of microbiologyno. 6 (2024): 268-268
Shaimaa A. Shehata,Eman Kolieb,Dina A. Ali,Shymaa Ahmed Maher, Horeya Erfan Korayem,Mahrous A. Ibrahim,Mohamed S. Nafie, Shimaa H. Ameen
Environmental Science and Pollution Researchno. 1 (2024): 458-480
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