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Bio
Professor Moffatt’s original GWAS study of 1,000 cases of childhood asthma and 1,000 controls identified the ORMDL3 locus on chromosome 17q21 as a major susceptibility gene. This locus is now recognised to be the strongest and most consistent genetic association to childhood asthma and has a central role in susceptibility to viral-induced asthma exacerbations. In 2010 she and Cookson coordinated the GABRIEL GWAS for asthma that involved 26,000 in 17 countries, and identified the other major genetic variants regulating asthma risk. Several of these are now the target for asthma therapies.
Prof. Moffatt has always been keenly interested in the mentorship and support of early-career scientists. Whilst a Junior Research Fellow at Green College Oxford she initiated a postgraduate research network that continues to the present day. She takes great pride in the achievements of the 40 postgraduate students (either basic scientists or Clinical Research Fellows), she has successfully supervised so far in her career. Consequently, she was delighted to be awarded the Imperial College President’s Medal for Outstanding Contribution to Research Supervision Excellence in 2014.
Research Interests
Papers共 391 篇Author StatisticsCo-AuthorSimilar Experts
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Chih-Yung Chiu,Saffron A. G. Willis-Owen, Kenny C.C. Wong, Stuart N. Farrow,William O.C. Cookson,Miriam F. Moffatt,Youming Zhang
Journal of Inflammationno. 1 (2024): 1-10
Ziyin Wang,Leah F Cuthbertson, Chubicka Thomas,Hadijatou J Sallah,Lucy G Mosscrop, Haoyuan Li,Tiina Talts,Kartik Kumar,Miriam F Moffatt,John S Tregoning
Mucosal immunologyno. 2 (2024): 272-287
Communications Biologyno. 1 (2024): 1-14
Journal of Cystic Fibrosisno. 2 (2023): 320-326
THORAXno. SUPPL_4 (2023): A105-A106
THORAXno. SUPPL_4 (2023): A38-A38
CELL REPORTS MEDICINEno. 10 (2023): 101226-101226
A. Nastase,A. Mandal, Y. Z. Zhang,J. Ish-Horowicz, S. Wilkinson, L. L. Lazdunski,A. G. Nicholson,D. Morris-Rosendahl,M. F. Moffatt,W. O. C. M. Cookson
THORAXno. SUPPL_4 (2023): A41-A41
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2023)
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THORAXno. SUPPL_4 (2023): A105-A105
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