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个人简介
Her major scientific interest resides in the understanding of the mechanisms of prompt resolution of type 2 diabetes and insulin resistance after upper gut bypass in subjects with obesity. She studies how insulin sensitivity - measured with the euglycaemic hyperinsulinemic clamp and stable isotope infusion or with the hyperglycaemic clamp to compute also insulin secretion - modifies following bariatric surgery in subjects with obesity and various states of glucose tolerance, from normal glucose tolerance to impaired glucose tolerance, and to frank diabetes. She also investigates the pathophysiology of non-alcoholic fatty liver disease (NASH) and non-alcoholic steato-hepatitis (NASH) in rodents and in humans after diet manipulations as well as after bariatric surgery.
Recently, she took part in the international team, including 5 scientists from the European Union and 5 scientists from the United States, which issued the EASD/ADA conjunct guidelines for the treatment of type 2 diabetes.
Techniques used are euglycaemic hyperinsulinemic clamp, hyperglycaemic clamp, intravenous glucose tolerance test, hypoglycemic clamp, indirect calorimetry, body composition. Her team benefits of the valuable contribution of trained biologists and technicians, who study the insulin signalling in human and rodent biopsies as quell as in primary culture cells. Statisticians and mathematicians elaborate the experimental results calculating insulin sensitivity and insulin secretion by using sophisticate mathematical models.
Recently, she took part in the international team, including 5 scientists from the European Union and 5 scientists from the United States, which issued the EASD/ADA conjunct guidelines for the treatment of type 2 diabetes.
Techniques used are euglycaemic hyperinsulinemic clamp, hyperglycaemic clamp, intravenous glucose tolerance test, hypoglycemic clamp, indirect calorimetry, body composition. Her team benefits of the valuable contribution of trained biologists and technicians, who study the insulin signalling in human and rodent biopsies as quell as in primary culture cells. Statisticians and mathematicians elaborate the experimental results calculating insulin sensitivity and insulin secretion by using sophisticate mathematical models.
研究兴趣
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Cell stress & chaperonesno. 2 (2024): 217-226
Peptidespp.171216-171216, (2024)
The Journal of clinical investigationno. 12 (2024)
Diabetes Research and Clinical Practice (2024): 111651-111651
Endocrinology Gut Microbiome, Microbial Metabolites and Cardiometabolic Riskpp.1-29, (2024)
Giulia Angelini,Manoel Galvao Neto, Ivo Boskoski,Maria Emiliana Caristo,Sara Russo, Luca Proto,Elena Previti,Lisa Olsson, Hobby Aggarwal,Samantha Pezzica, Elisa Ferrari,Vincenzo Bove,
GUTno. 4 (2024): 568-572
LIVER INTERNATIONALno. 3 (2024): 848-864
Sepehr Golriz Khatami,Astghik Sargsyan,Maria Francesca Russo,Daniel Domingo-Fernandez,Andrea Zaliani, Abish Kaladharan, Priya Sethumadhavan,Sarah Mubeen,Yojana Gadiya,Reagon Karki,Stephan Gebel, Ram Kumar Ruppa Surulinathan,
DATAno. 2 (2024): 25
Celine B.E. Busch,Suzanne Meiring,Annieke C.G. van Baar,Amalia Gastaldelli,Ralph DeFronzo,Geltrude Mingrone, Moira Hagen,Kelly White,Harith Rajagopalan, Max Nieuwdorp,Jacques J.G.H.M. Bergman
Gastrointestinal Endoscopy (2024)
METABOLISM-CLINICAL AND EXPERIMENTAL (2024): 155721-155721
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