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When facing to stress, the majority of individuals develop resilient responses to cope with aversive conditions. Unfortunately, negative strategies often induced in susceptible ones. Tremendous evidence shown that susceptibility to stress plays a central role in modulating the development of depressive disorders, my current aims are to investigate the brain reward circuits such as mPFC, lateral habenula (LHb), dorsal raphe (DRN) , ventral tegmental area (VTA) and related circuit-specific neural dysfunctions involved in regulating susceptibility to stress-related mental disorders as well as the underlying genetic/synaptic mechanisms by which lead to maladaptive behavioral responses to stress. My long-term goal is to understand how circuit/molecular/synaptic dysfunctions in certain brain regions give rise to stress-related behavioral deficiencies and I am strongly motivated in pursuit of yielding valuable insights for translational research such as anxiety and depression in humans.
Research Interests
Papers共 10 篇Author StatisticsCo-AuthorSimilar Experts
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Molecular neurobiology (2024)
Shiquan Wang, Liang Yu,Haiyun Guo, Wenqiang Zuo,Yaru Guo,Huiqing Liu,Jiajia Wang,Jin Wang,Xia Li,Wugang Hou,Minghui Wang
Molecular Neurobiologypp.1-20, (2024)
Science China. Life sciencesno. 1 (2023): 1-16
You Li,Zhenhua Jiang,Wenqiang Zuo, Chenchen Huang,Jianshuai Zhao, Peizheng Liu,Jiajia Wang, Jingzhi Guo,Xiao Zhang,Minghui Wang, Yan Lu,Wugang Hou,
Journal of neurochemistry (2023)
Biological Psychiatry (2022)
Mario Penzo, Valérie Robert,Jason Tucciarone,Dimitri De Bundel,Minghui Wang,Linda Van Aelst,Martin Darvas,Luis F. Parada,Richard D. Palmiter,Miao He, Zirui Huang,Bo Li
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