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Transcriptional regulatory pathways in stem cell and germ cell development; Biological functions of nonsense-mediated RNA decay (NMD), a conserved and selective RNA turnover pathway that functions in early embryonic development, neural development, and neural functions.
Pathways/processes: Transcription, epigenetics (DNA methylation and histone modifications), RNA splicing, RNA stability, NMD RNA surveillance pathway
Teams/collaborations: n/a
Approaches: KO and KD mice, genome-wide gene expression, reproductive organs, stem cells, neural progenitors
Diseases: X-linked mental retardation, diseases caused by nonsense and frameshift mutations
Transcriptional regulatory pathways in stem cell and germ cell development; Biological functions of nonsense-mediated RNA decay (NMD), a conserved and selective RNA turnover pathway that functions in early embryonic development, neural development, and neural functions.
Pathways/processes: Transcription, epigenetics (DNA methylation and histone modifications), RNA splicing, RNA stability, NMD RNA surveillance pathway
Teams/collaborations: n/a
Approaches: KO and KD mice, genome-wide gene expression, reproductive organs, stem cells, neural progenitors
Diseases: X-linked mental retardation, diseases caused by nonsense and frameshift mutations
Research Interests
Papers共 210 篇Author StatisticsCo-AuthorSimilar Experts
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crossref(2023)
Andrologyno. 5 (2023): 891-903
crossref(2023)
Cancer Researchno. 5 (2023): 1836-1843
Tiina Lehtiniemi,Matthieu Bourgery,Lin Ma,Ammar Ahmedani,Margareeta Makela, Juho Asteljoki,Opeyemi Olotu, Samuli Laasanen,Fu-Ping Zhang,Kun Tan,Jennifer N. Chousal,Dana Burow,
Milad Mortazavi,Yangsu Ren,Shubham Saini,Danny Antaki,Celine L. St. Pierre,April Williams,Abhishek Sohni,Miles F. Wilkinson, Meliss Gynrek,Jonathan Sebat, Abraham A. Palmer
CELL GENOMICSno. 3 (2022): 100102-100102
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