Michalina Maria Wezyk

基本信息

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职业迁徙

个人简介

Hi Everyone, I'm working on Alzheimer's disease functional phenotyping based on patients derived cerebral organoids. My major target is preclinical, presymptomatic disease stage and DNA damage driven dysfunction: the latest focus is at the synapse.

研究兴趣

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A Novel MAPK1 Variant in a Family with Complex Psychiatric and Neurodegenerative Clinical Phenotype

Wojciech Pokrzywa, Abhishek Dubey,Malgorzata Rydzanicz,Anna Barczak,Natalia Szulc, Bartłomiej Surpeta,Bozena Kuzniewska,Katarzyna Gaweda-Walerych,Michalina Wężyk,Mariusz Berdyński,Jakub Fichna,Grażyna Kostrzewa,Piotr Gasperowicz,Iwona Stępniak,Krystyna Szymańska,Krzysztof Szczałuba, Jan Brezovsky,Magdalena Dziembowska,Rafal Ploski

crossref（2025）

引用0浏览0引用

Rare A360T Mutation Alters GSK3β(Ser9) Binding in the Cytosolic Loop of Presenilin 1, Influencing Β-Catenin Nuclear Localization and Pro-Death Gene Expression in Alzheimer’s Disease Case

Michalina Wezyk,Mariusz Berdynski, Adam Figarski,Magdalena Skrzypczak,Krzysztof Ginalski,Marzena Zboch,Izabela Winkel,Cezary Zekanowski

International Journal of Molecular Sciencesno. 23 (2023): 16999-16999

引用0浏览0WOS引用

Oxidative DNA Damage Signalling in Neural Stem Cells in Alzheimer's Disease

Marcelina Kieroń,Cezary Żekanowski,Anna Falk,Michalina Wężyk

Oxidative medicine and cellular longevity（2019）

引用14浏览0WOS引用

Role of BRCA1 in Neuronal Death in Alzheimer’s Disease

M. Wezyk,C. Zekanowski

ACS Chemical Neuroscience（2018）

引用18浏览0WOS引用

Functional Characterization of a Novel Progranulin Mutation in a Patient with Progressive Nonfluent Aphasia

Katarzyna Gaweda-Walerych,Emilia J. Sitek,Ewa Narozanska,Michalina Wezyk,Bogna Brockhuis,Cezary Zekanowski,Jarosaw Slawek

Neurobiology of Aging（2018）

引用3浏览0WOS引用

Wild-type P53 Oligomerizes More Efficiently Than P53 Hot-Spot Mutants and Overcomes Mutant P53 Gain-of-function Via a “Dominant-Positive” Mechanism

Dawid Walerych,Magdalena Pruszko, Lukasz Zyla,Michalina Wezyk,Katarzyna Gaweda-Walerych,Alicja Zylicz

Oncotarget（2018）

引用12浏览0WOS引用

DNA Methylation in ELOVL2 and C1orf132 Correctly Predicted Chronological Age of Individuals from Three Disease Groups

M. Spólnicka,E. Pośpiech,B. Pepłońska,R. Zbieć-Piekarska, Ż. Makowska, A. Pięta,J. Karłowska-Pik,B. Ziemkiewicz,M. Wężyk,P. Gasperowicz,T. Bednarczuk,M. Barcikowska,C. Żekanowski,R. Płoski,Wojciech Branicki

International Journal of Legal Medicine（2018）

引用74浏览0WOS引用

What Factors Determine Phenotype of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)? Considerations in the Context of a Novel Pathogenic R110C Mutation in the NOTCH3 Gene

Dorota Dziewulska,Dorota Sulejczak,Michalina Wezyk

Folia Neuropathologica（2017）

引用9浏览0WOS引用

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论文共 11 篇作者统计合作学者相似作者