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Dr. Weiner’s research activities involve the development and utilization of MRI and PET for investigating and diagnosing neurodegenerative diseases. In 1980, Dr. Weiner was one of the first to perform MRS on an intact animal, and subsequently pursued his goal to develop MRI/S as a clinical tool. In 1988, his group used MRS to show that the amino acid N acetyl aspartate (NAA), a marker of healthy nerve cells, is reduced in the epileptic focus in the brain. In 2004, Dr. Weiner's group reported that reduced NAA predicts development of Alzheimer's disease in mildly impaired elderly subjects. During the past 25 years he has worked to develop and optimized the use of MRI, PET, and blood based biomarker methods to diagnose Alzheimer’s disease and other neurodegenerative disorders. Also, Dr. Weiner’s research focuses on monitoring effects of treatment to slow progressions in Alzheimer’s disease, and detecting Alzheimer’s disease early in patients who are not demented, but risk subsequent development of dementia.
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Anna Aaronson,Miriam T. Ashford,Chengshi Jin,Jessica Bride, Josephine Decker, Aaron DeNicola,Robert W. Turner, Catherine Conti, Rachana Tank, Diana Truran,Monica R. Camacho,Juliet Fockler,
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bioRxiv : the preprint server for biology (2024)
NEUROIMAGE (2024): 120494-120494
crossref(2024)
Archives of Clinical Neuropsychologyno. 5 (2023): 739-758
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