1980 B. Sc. (Hons.), Australian National University。 1985 D. Phil., Oxford University, UK。 1986-1991 Staff Scientist, European Molecular Biology Laboratory, Heidelberg, Germany。 1991-1996 Welcome Australian Senior Research Fellow, SVI。 1996-2000 Australian Research Council Senior Research Fellow, SVI。 2000-2001 Australian Research Council Professorial Research Fellow。 2002-2006 National Health & Medical Research Council Senior Principal Research Fellow。 2007-2011 Australian Research Council Federation Fellow。 1991 Wellcome Trust Senior Research Fellowship。 1994 University of Melbourne Selwyn-Smith Medical Research Prize。 1996 ASBMB Boehringer-Mannheim Medallist。 1997 Australian Research Council Senior Research Fellowship。 1999 Gottschalk Medal of the Australian Academy of Science。 2001 NHMRC Senior Principal Research Fellowship。 2004 GE Healthcare Bio-Sciences Award of the ASBMB。 2006 Australian Research Council Federation Fellowship。 2006 NHMRC Senior Principal Research Fellowship。 2010 Fellow of the Australian Academy of Science。 2011 ASBMB Lemberg Medal。 2011 NHMRC Senior Principal Research Fellowship。 2011 Ramaciotti Medal for Excellence in Biomedical Research。 2012 Federation of Asian and Oceanian Biochemists and Molecular Biologists Award for Research Excellence。 Research Interests： Protein crystallography; structure-based drug design; cancer; infection; neurobiology The ACRF Rational Drug Discovery Centre is focused on three disease areas: cancer, infection (bacterial toxins, parasites and viruses) and neurological diseases (Alzheimer's disease, memory loss, epilepsy, anxiety). Our aim is to understand the function of key proteins at a molecular level and to discover small molecules that alter the function of these proteins which may then be developed into clinically useful drugs. The lab uses a wide array of platform technologies including molecular biology, protein chemistry, protein characterisation tools, X-ray crystallography (including the Australian Synchrotron), electrophysiology, virtual screening and structure-based drug design. Selected Publications： Parker, M.W., Pattus, F., Tucker, A.D. & Tsernoglou, D. (1989) Structure of the membrane-pore-forming fragment of colicin A. Nature 337, 93-96. Parker, M.W., Buckley, J.T., Postma, J.P., Tucker, A.D., Leonard, K., Pattus, F. & Tsernoglou, D. (1994) Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states. Nature 367, 292-295. Hu, S.H., Parker, M.W., Lei, J.Y., Wilce, M.C., Benian, G.M. & Kemp, B.E. (1994) Insights into autoregulation from the crystal structure of twitchin kinase. Nature 369, 581-584. Rossjohn, J., Feil, S.C., McKinstry, W.J., Tweten, R.K. & Parker, M.W. (1997) Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form. Cell 89, 685-692.