基本信息
views: 0
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
In one facet of our research program, we study human population epigenetics aimed at deciphering the mechanisms by which environmental exposures and early-life experiences can "get under the skin" to regulate gene activity and contribute to health and disease across the life course. This research aligns with the Developmental Origins of Health and Disease (DOHaD) hypothesis, which postulates that the developmental period and early life are particularly sensitive periods where social or environmental insults can influence health long after the insult itself. Our findings support the model that early-life social and environmental factors, including stress and socioeconomic status, leave a biological footprint. We measure this biological embedding of early life exposures through epigenetic patterns and accompanying gene expression changes, many of which are maintained until adulthood and may influence future health. We have extensive interdisciplinary collaborations across Canada and around the world and are affiliated with multiple NCEs (including AllerGen and NeuroDevNet).
Research Interests
Papers共 422 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Aging cellpp.e14149-e14149, (2024)
Nature Mental Healthno. 1 (2024): 52-62
S L Schaffner, W Casazza, F Artaud, C Konwar, S M Merrill, C Domenighetti, J M Schulze-Hentrich, S Lesage, A Brice, J C Corvol, S Mostafavi, J K Dennis,
NPJ Parkinson's diseaseno. 1 (2024): 98-98
Research square (2024)
EPIGENOMESno. 1 (2024): 3
GeroSciencepp.1-13, (2024)
AGING CELL (2024)
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn