Dr. Yeaman is a pioneer in the discovery and development of innovative anti-infectives. The themes of his research program focus upon the relationship between host defense and microbial pathogenesis, including: 1) innate and adaptive immune memory as applied to vaccine discovery; 2) structure-activity relationships in host defense peptides as templates for novel anti-infectives; 3) new antimicrobialo targets such as quorum sensing and programmed cell death; and 4) discovering and applying the power of convergent immunity to breakthrough immunotherapeutics & strategies. Through such innovations, Dr. Yeaman focuses his medical science on meeting the challenge of antibiotic-resistant infections caused by priority and emerging pathogens to save and improve lives.