基本信息
views: 4
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
My research interests involve mechanistic studies of serious adverse drug reactions with a specific focus on drug hypersensitivity. Our group is working on determining the relative contributions of metabolism and immune response in the development of drug hypersensitivity to a number of drugs including commonly used antibiotics, anti-epilepsy drugs and chemotherapeutic agents. More recently we are investigating how genetically determined variations in drug metabolism, immune response, drug transport and cellular repair determine risk for serious adverse events to chemotherapy for childhood cancer. Our laboratory also has a long-standing interest in steroid biology and the impact of stress on corticosteroid production. We are also involved in a series of clinical studies to define optimal therapy for children in acute and emergency care settings. More recent areas of focus in our laboratory are studies on point of care diagnostics for food and drug safety and in the development of wireless sensor systems for the evaluation of pharmacological responses.
Research Interests
Papers共 429 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Journal of pharmacological and toxicological methodspp.107536-107536, (2024)
Sylvia Martinez-Cabriales,Jerome Coulombe,Michelle Aaron, Sadaf H. Hussain, Danny Linggonegoro,Irene Lara-Corrales,Hailey Barootes, Heather Brandling-Bennett, Isabela Covelli,Anna Yasmine Kirkorian,Nidhi Shah,Leslie Castelo-Soccio,
Naima Abouseta,Noha Gomaa,Ali Tassi,Abdelbaset A Elzagallaai,Michael J Rieder, S Jeffrey Dixon,Sharat Chandra Pani
Caries researchpp.1-10, (2024)
Richard J. Huntsman,Jesse Elliott,Evan Lewis,Charlotte Moore-Hepburn,Jane Alcorn,Holly Mansell, Juan P. Appendino,Richard E. Belanger,Scott Corley,Bruce Crooks, Anne Marie M. Denny,Yaron Finkelstein,
PAEDIATRICS & CHILD HEALTHno. 1 (2024): 12-16
COMPREHENSIVE PSYCHONEUROENDOCRINOLOGY (2024): 100231-100231
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2024)
Paediatrics & child healthno. 2 (2024): 104-121
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn