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Along with Dr. Lorne Tyrrell and a large team of experts within his academic lab and the Li Ka Shing Applied Virology Institute, Dr. Houghton is developing a vaccine against HCV by optimising both the production of cross-neutralising antibodies and cross-reactive cellular immune responses to the many different genotypes of HCV that occur around the world. Clinical trials are expected to be initiated in 2019.His laboratory has also discovered new blood biomarkers associated with autoimmune liver disease which will be tested for clinical diagnostic utility in 2018/9.He is also involved in other programs such as the discovery of new antivirals, anti-cancer agents and inhibitors of fatty liver disease, all incorporating state-of-art computational science allied with biomedical methods.
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of Americano. Supplement_3 (2023): S257-S261
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ACS applied materials & interfacesno. 25 (2023): 29914-29926
Lok Man John Law,Michael Logan,Michael Joyce,Abdolamir Landi,Darren Hockman,Kevin Crawford,Janelle Johnson,Gerald LaChance,Holly Saffran,Justin Shields, Eve Hobart,Raelynn Brassard,
crossref(2021)
John Lok Man Law,Michael Logan,Michael A Joyce,Abdolamir Landi,Darren Hockman,Kevin Crawford,Janelle Johnson, Gerald LaChance,Holly A Saffran,Justin Shields, Eve Hobart,Raelynn Brassard,
Maral Aminpour, Williams Ernesto Miranda Delgado,Soren Wacker, Sergey Noskov,Michael Houghton,D. Lorne J. Tyrrell,Jack A. Tuszynski
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