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个人简介
His research group focuses on how biologic therapy can be utilised as a molecular scalpel to understand the pathogenesis of autoimmune rheumatic disease, in particular systemic lupus erythematosus (SLE) and rheumatoid arthritis, both in terms of loss of immune tolerance and ongoing inflammation, to develop novel (and safer) therapies and improve existing therapies, and to target therapies to patients most likely to benefit through biomarker identification. He was chief investigator for the BEAT-LUPUS trial which arose from experimental medicine studies looking at the immune consequences of B cell depletion (rituximab) in patients with SLE, and was one of the first trials to test combination biologic therapy (belimumab after rituximab) for patients with SLE.
研究兴趣
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LANCET RHEUMATOLOGYno. 11 (2023): E648-E659
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The Lancet. Rheumatologyno. 11 (2023): e648-e659
RHEUMATOLOGY ADVANCES IN PRACTICEno. 1 (2023): rkae017-rkae017
Rheumatologyno. Supplement_2 (2023)
ARTHRITIS & RHEUMATOLOGYno. Supplement_2 (2023): 3421-3422
The Journal of experimental medicineno. 6 (2023)
RHEUMATOLOGY (2023)
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