Michael E Grimwood - Xenon Pharmaceuticals Inc

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Papers共 12 篇Author StatisticsCo-AuthorSimilar Experts

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The Contribution of NaV1.6 to the Efficacy of Voltage-Gated Sodium Channel Inhibitors in Wild Type and NaV1.6 Gain-of-function (GOF) Mouse Seizure Control

BRITISH JOURNAL OF PHARMACOLOGYno. 20 (2024): 3993-4011

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Author Response: NBI-921352, a First-in-class, NaV1.6 Selective, Sodium Channel Inhibitor That Prevents Seizures in Scn8a Gain-of-function Mice, and Wild-Type Mice and Rats

openalex（2022）

Cited26Views0Bibtex

NBI-921352, a First-in-class, NaV1.6 Selective, Sodium Channel Inhibitor That Prevents Seizures in Scn8a Gain-of-function Mice, and Wild-Type Mice and Rats

ELIFE (2022)

Cited31Views0WOSBibtex

Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- A]pyridin-3-yl)methane-sulfonamides As Potent and Selective Hnav1.7 Inhibitors for the Treatment of Pain

Journal of Medicinal Chemistry（2018）

Cited28Views0WOSBibtex

Selective Antagonists of Na(V)1.6 Prevent Electrically Induced Seizures in a Mouse Model of EIEE13

Parisa Tari,Celine Dube,Kuldip Khakh,Elaine Chang,Noah Shuart,Clint Young,Sophia Lin,Zhiwei Xie,Richard Dean, Andrea Lindgreen,Luis Sojo,Abid Hasan,Wei Gong,Michael Grimwood,Thilo Focken,Charles J. Cohen, Jr. Johnson J. P.

JOURNAL OF GENERAL PHYSIOLOGY（2016）

Cited0Views0Bibtex

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