He works as a paediatric infectious diseases consultant and has led research focused on the diagnosis and treatment of a range of childhood infections including meningococcal disease, tuberculosis, bacterial sepsis and Kawasaki disease. He currently leads the EU funded PERFORM study investigating the application of RNA transcriptomics to improve diagnosis of childhood infection. He also leads the NIH funded study Validation of Biomarkers of Pediatric TB and further development for use in diagnosis of childhood TB.