Michael A. Mcdonough - The Department of Chemistry and the Oxford Centre for Integrative Systems Biology, University of Oxford

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论文共 149 篇作者统计合作学者相似作者

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Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma Mansoni Survival, Oviposition, and Development

Matthias Schiedel,Darius J. B. McArdle,Gilda Padalino,Anthony K. N. Chan,Josephine Forde-Thomas,Michael McDonough,Helen Whiteland,Manfred Beckmann,Rosa Cookson,Karl F. Hoffmann,Stuart J. Conway

JOURNAL OF MEDICINAL CHEMISTRYno. 23 (2023): 15801-15822

引用2浏览0WOS引用

Structural Basis for Binding of the Renal Carcinoma Target Hypoxia‐inducible Factor 2α to Prolyl Hydroxylase Domain 2

William D. Figg Jr,Giorgia Fiorini,Rasheduzzaman Chowdhury,Yu Nakashima,Anthony Tumber,Michael A. McDonough,Christopher J. Schofield

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICSno. 11 (2023): 1510-1524

引用5浏览0WOS引用

Mutate and Conjugate: A Method to Enable Rapid In-Cell Target Validation

Adam M. Thomas,Marta Serafini,Emma K. Grant, Edward A. J. Coombs,Joseph P. Bluck,Matthias Schiedel,Michael A. Mcdonough,Jessica K. Reynolds,Bernadette Lee, Michael Platt, Vassilena Sharlandjieva,Philip C. Biggin,Fernanda Duarte,Thomas A. Milne,Jacob T. Bush,Stuart J. Conway

ACS Chemical Biology（2023）

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In Vitro Selection of Macrocyclic Peptide Inhibitors Containing Cyclic Γ2,4-Amino Acids Targeting the SARS-CoV-2 Main Protease

Takashi Miura,Tika R. Malla,C. David Owen,Anthony Tumber,Lennart Brewitz,Michael A. McDonough,Eidarus Salah,Naohiro Terasaka,Takayuki Katoh,Petra Lukacik,Claire Strain-Damerell,Halina Mikolajek,Martin A. Walsh,Akane Kawamura,Christopher J. Schofield,Hiroaki Suga

NATURE CHEMISTRYno. 7 (2023): 998-+

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Oligonucleotide analogues with locked-amide linkages have therapeutic potential

Ysobel Baker,Cameron Thorpe,Jinfeng Chen, Laura Poller, Lina Cox,Pawan Kumar,Wooi Fang Lim, Lillian Lie,Graham McClorey,Sven Epple,Daniel Singleton,Michael McDonough,Jack Hardwick,Kirsten Christensen,Matthew Wood,James Hall,Afaf El-Sagheer,Tom Brown

Research Square (Research Square) (2022)

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An LNA-amide Modification That Enhances the Cell Uptake and Activity of Phosphorothioate Exon-Skipping Oligonucleotides

Ysobel R. Baker,Cameron Thorpe,Jinfeng Chen, Laura M. Poller, Lina Cox,Pawan Kumar,Wooi F. Lim, Lillian Lie,Graham McClorey,Sven Epple,Daniel Singleton,Michael A. McDonough,Jack S. Hardwick,Kirsten E. Christensen,Matthew J. A. Wood,James P. Hall,Afaf H. El-Sagheer,Tom Brown

Nature Communications（2022）

引用20浏览0WOSNATURE引用

Mechanisms of Substrate Recognition and N6-methyladenosine Demethylation Revealed by Crystal Structures of ALKBH5–RNA Complexes

Simranjeet Kaur,Nok Yin Tam,Michael A. McDonough,Christopher J. Schofield,Wei Shen Aik

NUCLEIC ACIDS RESEARCHno. 7 (2022): 4148-4160

引用41浏览0WOS引用

Studies on the Reactions of Biapenem with VIM Metallo Β-Lactamases and the Serine Β-Lactamase KPC-2

Anka Lucic,Tika R. Malla,Karina Calvopina,Catherine L. Tooke,Jurgen Brem,Michael A. McDonough,James Spencer,Christopher J. Schofield

ANTIBIOTICS-BASEL（2022）

引用8浏览0WOS引用

In Situ Inhibitor Synthesis and Screening by Fluorescence Polarization: an Efficient Approach for Accelerating Drug Discovery

Zhihong Li,Yue Wu,Shuai Zhen,Kaijun Su,Linjian Zhang,Fulai Yang,Michael A. McDonough,Christopher J. Schofield,Xiaojin Zhang

Angewandte Chemie International Edition（2022）

引用14浏览0WOS引用

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