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Bio
Dr. Gregory-Ksander has a longstanding interest in how age-related changes in immune privilege and subsequent inflammation contributes to the development of ocular disease. The current research in Dr. Gregory-Ksander’s lab at Schepens Eye Research Institute at Mass. Eye and Ear is specifically focused on how age-related changes in immune privilege and subsequent inflammation contributes to the development of glaucoma and age-related macular degeneration (AMD). Using animal models of glaucoma and AMD, Dr. Gregory-Ksander has identified Fas ligand (FasL) and the NLRP3 inflammasoma as two critical mediators of ocular inflammation and current studies focus on how age-related changes in FasL and the NLRP3 inflammasome contribute to the development of inflammation associated with glaucoma and AMD.
Research Interests
Papers共 110 篇Author StatisticsCo-AuthorSimilar Experts
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 4 (2024): 2307
Bruce Ksander,Madhura Shah,Drenushe Krasniqi,Meredith S. Gregory-Ksander, Sharon Rosenzweig-Lipson, Kasia Broniowska,Michel Wathier,Joan Mannick, Jennifer Cermak,Margarete Karg,Shintaro Shirahama,Nasrin Refaian,
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2023): 1265471-1265471
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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Cellular reprogrammingno. 6 (2023): 288-299
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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