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Bio
He started to work in this area more than 15 years ago and performed in 2000 the first human intramyocardial transplantation of autologous skeletal myoblasts in a patient with severe heart failure. He was then the PI of a randomised controlled trial of myoblast transplantation designed to assess the safety and efficacy of the technique. The suboptimal results of this study has then led the group to refocus on the use of cardiac progenitors derived from human embryonic stem cells (ESC). The laboratory is using small and large animal (including nonhuman primate) models of myocardial infarction and, in parallel with basic and preclinical studies on myocardial regeneration by ESC-derived cardiac progenitors, is involved in the optimisation of cell delivery and survival-enhancing techniques through the use of tissue engineering with the objective of an upcoming clinical translation in patients with end-stage heart failure who have exhausted conventional therapies.
Research Interests
Papers共 247 篇Author StatisticsCo-AuthorSimilar Experts
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EBIOMEDICINE (2024): 105145-105145
Aline Derisio de Lima,Hernán González‐King Garibotti, Myriam Assal, Assia Haddouche,Valérie Bellamy, Qing Dong Wang,Cecilia Granéli,Makoto Miyara,Jean‐Sébastien Silvestre,Karin Jennbacken,Philippe Menasché
Circulationno. Suppl_1 (2023)
Frontiers in cardiovascular medicine (2023)
Journal of the American College of Cardiologyno. 9 (2023): 864-866
Journal of molecular and cellular cardiology (2023): 14-21
Circulationno. Suppl_1 (2022)
Chloe Pezzana,Audrey Cras,Fanny Simeliere, Rose Guesdon,Manon Desgres,Bruna Lima Correa,Ashley Peuffier,Valerie Bellamy, Sara Gouarderes,Antonio Alberdi,Marie-Cecile Perier,Laetitia Pidial,
BIOMATERIALS (2022): 121877-121877
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Author Statistics
#Papers: 243
#Citation: 14591
H-Index: 59
G-Index: 117
Sociability: 7
Diversity: 4
Activity: 69
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