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Acquired immunity to foreign pathogens depends on the differentiation of B and T lymphocytes from hematopoietic stem cells, which is controlled by a multitude of transcription factors. We are interested in understanding the process by which transcription factors regulate the commitment of early hematopoietic progenitors to the B cell lineage and control their subsequent differentiation to mature B cells and plasma cells. We investigate the underlying transcriptional control mechanisms by using mouse transgenic, cell biological, and genome-wide molecular approaches.
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论文共 253 篇作者统计合作学者相似作者
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Ariane Mandlbauer,Qiong Sun,Niko Popitsch,Tanja Schwickert, Miroslava Spanova,Jingkui Wang,Stefan L Ameres,Meinrad Busslinger,Luisa Cochella
The EMBO journal (2024)
Yi-Feng Gu, Shannon Cohn,Alana Christie,Tiffani McKenzie,Nicholas Wolff,Quyen N. Do,Ananth J. Madhuranthakam,Ivan Pedrosa,Tao Wang, Anwesha Dey,Meinrad Busslinger,Xian-Jin Xie,
crossref(2023)
JOURNAL OF EXPERIMENTAL MEDICINEno. 1 (2022)
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