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Bio
Mehrnoosh Ghiam, PhD, specializes in identifying specific molecular corneal defects associated with corneal pathological conditions such as diabetes. Her work employs a variety of molecular, functional tests and ex-vivo human organ-cultured corneas to understand the role of microRNAs in both the differentiated epithelial and stem cells of normal, and diabetic corneas and their roles in driving peripheral activation of limbal stem cells in normal and diseased corneas. In addition, she investigates the major mechanisms of action of nano-sized limbal extracellular vesicles (EVs), which are taken up by neighboring cells, in stem cell maintenance and wound repair in cell cultures and in normal and diabetic human organ-cultured corneas, and the therapeutic potential of EVs for treatment of corneal injuries and diabetic abnormalities.
Research Interests
Papers共 89 篇Author StatisticsCo-AuthorSimilar Experts
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Nagendra Verma,Adam Poe, Andrew Fealy, Mariam Ebrahami, Anokhi Patel, Ying Xue,Santiskulvong Chintda,Alex Rajewski, Sun Ren, Kevin Tseng,Sungyong You,Alexander Ljubimov,
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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Diabetologiano. 10 (2023): 1943-1958
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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Progress in Retinal and Eye Research (2023): 101149-101149
Nagendra Verma,Drirh Khare,Adam J. Poe,Cynthia Amador,Sean Ghiam, Andrew Fealy, Shaghaiegh Ebrahimi, Odelia Shadrokh,Xue-Ying Song,Chintda Santiskulvong,Mitra Mastali,Sarah Parker,
Cellsno. 21 (2023): 2524-2524
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