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The mechanisms by which multi-nucleated osteoclasts stimulate osteoblastic bone formation in order to identify therapeutic targets to promote bone formation in aging and cancer-induced bone disease.
Our lab profiles the mechanisms by which multi-nucleated osteoclasts stimulate osteoblastic bone formation in order to identify novel therapeutic targets to promote bone formation in aging and cancer-induced bone disease. We use cell culture and animal models to dissect out osteo-immunology signaling pathways differentially regulated in osteoclast resorption and stimulation of bone formation. We are working across disciplines (engineering, materials science, pharmacy, medicine) to develop novel tools to study resorption and single cell osteoclast dynamics.
The mechanisms by which multi-nucleated osteoclasts stimulate osteoblastic bone formation in order to identify therapeutic targets to promote bone formation in aging and cancer-induced bone disease.
Our lab profiles the mechanisms by which multi-nucleated osteoclasts stimulate osteoblastic bone formation in order to identify novel therapeutic targets to promote bone formation in aging and cancer-induced bone disease. We use cell culture and animal models to dissect out osteo-immunology signaling pathways differentially regulated in osteoclast resorption and stimulation of bone formation. We are working across disciplines (engineering, materials science, pharmacy, medicine) to develop novel tools to study resorption and single cell osteoclast dynamics.
Research Interests
Papers共 92 篇Author StatisticsCo-AuthorSimilar Experts
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Journal of Bone Oncology (2024): 100620
Current Osteoporosis Reportspp.1-12, (2024)
Boya Zhang,William Benton Swanson,Margaret Durdan, Heather N. Livingston,Michaela Dodd,Sachith M. Vidanapathirana,Alec Desai, Lindsey Douglas,Yuji Mishina,Megan Weivoda,Colin F. Greineder
JOURNAL OF BONE AND MINERAL RESEARCH (2024)
Angelo Jose Guilatco,Marta Diaz-del-Castillo,Gabriel Alvares Borges, Neal I. Sannuli, Megan L. Ritting, Syed Mohammed Aalam,Nagarajan Kannan,Tamar Tchkonia,James L. Kirkland,Yi Lin,Taxiarchis Kourelis,Matthew T. Drake,
Cancer Researchno. 6_Supplement (2024): 2958-2958
Blood (2023): 90
Nadine Abdallah, Paul DiZona,Amanika Kumar,Betsy LaPlant, Terri Menser, Sarah Aug,Megan Weivoda,Joselle Cook,Francis Buadi,Suzanne R. Hayman,Angela Dispenzieri,Martha Lacy,
Blood (2023): 1986
JOURNAL OF BONE AND MINERAL RESEARCH (2023): 208-208
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Gwenyth J. Joseph,Lawrence A. Vecchi,David Kell,Sasidhar Uppuganti,Margaret Durdan, Wei Chen,David Harrison,Jeffry S. Nyman,Megan Weivoda,Rachelle W. Johnson
JOURNAL OF BONE AND MINERAL RESEARCH (2023): 53-53
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