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个人简介
He was previously a Clinical Fellow in the Combined Pediatrics-Genetics Residency Training Program at Boston Children’s Hospital. He is originally from New Jersey and obtained an MD and PhD from the University of California, San Francisco. During his PhD research, he developed tools based on CRISPR technology that enable researchers to systematically turn genes on and off in order to discover new gene functions. Through this work and his medical school training, he came to appreciate the vast gap between our ability to read the DNA of patients and our understanding of how small spelling changes can lead to the broad range of symptoms that affect people living with rare disease. This inspired him to join Boston Children’s Hospital for Pediatrics Residency and is now completing the Genetics Fellowship portion of his training.
His current research focuses on using the CRISPR-based tools he developed to generate a large-scale map of the genes involved in modifying chromatin and their role in regulating target genes, with the ultimate goal of better understanding and treating disorders of epigenetic dysregulation.
His current research focuses on using the CRISPR-based tools he developed to generate a large-scale map of the genes involved in modifying chromatin and their role in regulating target genes, with the ultimate goal of better understanding and treating disorders of epigenetic dysregulation.
研究兴趣
论文共 64 篇作者统计合作学者相似作者
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Yan Hu,Max A. Horlbeck,Ruochi Zhang,Sai Ma,Rojesh Shrestha,Vinay K. Kartha,Fabiana M. Duarte, Conrad Hock, Rachel E. Savage,Ajay Labade,Heidi Kletzien, Alia Meliki, Andrew Castillo,Neva C. Durand,Eugenio Mattei, Lauren J. Anderson,Tristan Tay,Andrew S. Earl,Noam Shoresh,Charles B. Epstein,Amy J. Wagers,Jason D. Buenrostro
NATURE (2025)
Proceedings of the National Academy of Sciencesno. 22 (2024)
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bioRxiv the preprint server for biology (2024)
Patricia Borck,Kirsty Wienand,Fabiana Duarte, Alvin Qin,Ruochi Zhang, Juliana Babu, Simone Zhang, Samuel Maffa,Max Horlbeck,Rojesh Shrestha,Joshua Dempster,Jennifer Roth,Catarina Campbell,Jason Buenrostro,Francisca Vazquez
Cancer Researchno. 7_Supplement (2024): LB234-LB234
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Marcela C. Briones Martin del Campo,Alex Lee,Max Horlbeck, Truc Dinh, Marta Roman-Moreno,Leanne Sayles, Bokyung Seong,Kimberly Stegmaier,Luke Gilbert,E. Alejandro Sweet-Cordero
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CLINICAL CANCER RESEARCHno. 18 (2022)
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David Wu,Aunoy Poddar, Elpiniki Ninou,Elizabeth Hwang,Mitchel A. Cole,S. John Liu,Max A. Horlbeck,Jin Chen,Joseph M. Replogle,Giovanni A. Carosso, Nicolas W. L. Eng, Jonghoon Chang,Yin Shen,Jonathan S. Weissman,Daniel A. Lim
Cell Genomicsno. 11 (2022): 100177-100177
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作者统计
#Papers: 64
#Citation: 9007
H-Index: 25
G-Index: 38
Sociability: 6
Diversity: 2
Activity: 4
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