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个人简介
During my MSc and PhD I performed studies on the role of cyclooxygenase-2 and prostaglandin E2 signaling in the seizures induced by pentylenetetrazol, by using electroencephalographical, pharmacological and neurochemical methods. The main conclusion of these studies was that cyclooxigenase-2 and prostaglandin E2 facilitate pentylenetetrazol-induced seizures, and that the molecular mechanism underlying such effects involves prostaglandin EP receptors, which ultimately decrease Na+,K+-ATPase activity by causing enzyme phosphorylation.
Part of my PhD research was developed under the supervision of Dr. Emilio Rafael Garrido-Sanabria in the University of Texas at Brownsville, where I learned the pilocarpine model of epilepsy and received training in several electrophysiological and molecular biology methods.
Currently I hold a permanent position as a professor at the Universidade Federal de Santa Maria. In my lab we are focusing on the pilocarpine model of epilepsy as a tool to investigate basic mechanisms in epilepsy and related comorbities. To this purpose, at present I am performing several behavioral tests in pilocarpine-epileptic C57BL/6 mice and analyzing the expression and function of selected receptors and transporters in these subjects.
研究兴趣
论文共 158 篇作者统计合作学者相似作者
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ACS Chemical Neuroscienceno. 15 (2024): 2695-2702
Vitamins and hormones (2024): 125-168
Brain sciencesno. 3 (2023): 386-386
Journal of Nanoparticle Researchno. 1 (2023): 1-10
Ana Claudia Monteiro Braga,Naieli Schiefelbein Souto,Fernanda Licker Cabral,Micheli Dassi,Érica Vanessa Furlan Rosa, Naiara dos Santos Guarda, Luiz Fernando Freire Royes, Michele Rechia Fighera,Rafael Noal Moresco,Mauro Schneider Oliveira,Marcel Henrique Marcondes Sari, Ana Flávia Furian
Brain Sciencesno. 3 (2023): 386
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作者统计
#Papers: 155
#Citation: 2937
H-Index: 32
G-Index: 45
Sociability: 6
Diversity: 4
Activity: 31
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