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Description of Research Expertise
The overarching goal of the Hayes lab is to identify and characterize the neural signaling pathways controlling for food intake and body weight regulation in an effort to treat obesity and associated co-morbidities. To this end, our research examines the behavioral, intracellular, neuronal and endocrine mechanisms governing energy balance and how these processes are dysregulated in obesity.
A major theme of research in our lab focuses on the neuropeptide glucagon-like peptide-1 (GLP-1) and its role in regulating energy balance through action in the periphery on the vagus nerve (cranial nerve X), as well as the central nervous system (CNS). The potential for GLP-1 receptor agonists to be used as a pharmacological treatment for obesity has been highlighted in a number of recent publications. For this to become a reality, however, will require a deepened understanding of the behavioral, neuronal, and physiological mechanisms by which the peripheral and central GLP-1 systems control for food intake and body weight regulation.
The overarching goal of the Hayes lab is to identify and characterize the neural signaling pathways controlling for food intake and body weight regulation in an effort to treat obesity and associated co-morbidities. To this end, our research examines the behavioral, intracellular, neuronal and endocrine mechanisms governing energy balance and how these processes are dysregulated in obesity.
A major theme of research in our lab focuses on the neuropeptide glucagon-like peptide-1 (GLP-1) and its role in regulating energy balance through action in the periphery on the vagus nerve (cranial nerve X), as well as the central nervous system (CNS). The potential for GLP-1 receptor agonists to be used as a pharmacological treatment for obesity has been highlighted in a number of recent publications. For this to become a reality, however, will require a deepened understanding of the behavioral, neuronal, and physiological mechanisms by which the peripheral and central GLP-1 systems control for food intake and body weight regulation.
Research Interests
Papers共 240 篇Author StatisticsCo-AuthorSimilar Experts
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Contact (Thousand Oaks (Ventura County, Calif.)) (2024): 25152564241239445-25152564241239445
American journal of physiology. Endocrinology and metabolismno. 4 (2024): E528-E536
ACS CHEMICAL BIOLOGY (2023)
Neuropharmacology (2023): 109686-109686
Neuropsychopharmacologyno. 13 (2023): 1878-1888
Gabriel Gonzalez,Matthew Hayes,Melinda Balansay, Ryan Underwood, Caroline Balagot,Roger Pan, Kyle Pineda, Esmeralda Iniguez-Stevens,Paula Kriner, Irais Estrada,Christopher A Myers,Adriana E Kajon
Journal of medical virologyno. 3 (2023)
Mohammed Asker,Jean‐Philippe Krieger, Amber Liles,Ian C. Tinsley,Tito Borner,Ivana Marić,Sarah Doebley, Charles D. Furst,Stina Börchers,Francesco Longo,Yashaswini R Bhat,Bart C. De Jonghe,
Diabetes, Obesity and Metabolismno. 3 (2023): 856-877
Physiology & Behavior (2023): 114236-114236
Samantha M. Fortin,Jack C. Chen, Marisa C. Petticord,Forrest J. Ragozzino,James H. Peters,Matthew R. Hayes
Science advancesno. 38 (2023)
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