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Bio
The Hill lab uses a range of cellular, biochemical and behavioural techniques to examine the role of the endocannabinoid system in the regulation of stress. Endocannabinoids are the brains endogenous version of THC, the psychoactive constituent of cannabis (similar to how endorphins are the body’s endogenous version of morphine). Research from us, and others, has demonstrated that endocannabinoid signalling is important for both the termination of the stress response and adaptation of the stress response under conditions of repeated exposure. We have found that under conditions of chronic stress, endocannabinoid signalling “breaks down”, and that the loss of this system may be one of the mechanisms by which chronic stress increases the risk of affective illnesses, such as depression and anxiety disorders. More recently, our work has integrated two components related to the developing brain. First, we are exploring how pre- and post-natal exposure to stress or inflammation impacts endocannabinoid function and alters the development of the endocannabinoid system. Second, we are also now exploring the impacts of prenatal exposure to cannabis and how this impacts neurodevelopmental processes.
Research Interests
Papers共 274 篇Author StatisticsCo-AuthorSimilar Experts
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Biological Psychiatry Global Open Scienceno. 1 (2024): 11-18
Landscape Ecologyno. 4 (2024): 1-18
Catherine Hume,Samantha L. Baglot,Lucia Javorcikova,Savannah H. M. Lightfoot, Jessica Scheufen,Matthew N. Hill
International Journal of Obesityno. 7 (2024): 1-12
Neurobiology of Stresspp.100662, (2024)
Journal of neuroscience researchno. 7 (2024): e25369-e25369
INSECT CONSERVATION AND DIVERSITYno. 2 (2024): 374-385
openalex(2024)
Psychological medicineno. 15 (2023): 7006-7024
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Author Statistics
#Papers: 279
#Citation: 13544
H-Index: 62
G-Index: 112
Sociability: 7
Diversity: 0
Activity: 3
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