Masashi Shimazaki - Department of Biological Information, Tokyo Institute of Technology

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论文共 20 篇作者统计合作学者相似作者

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1323 A Novel Bispecific Antibody Targeting CD137 and CLDN4 for Treating Patients with Solid Tumors

Masahito Sato,Aya Kikuchi, Keita Nagaoka, Sumito Yoshida, Nicholas Souders, Masayasu Yoshino,Masayo Oishi,Hiroyuki Sayama, Takeshi Saito,Masashi Shimazaki,Kenna Shirasuna

Regular and Young Investigator Award Abstracts (2024)

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Discovery of ASP6918, a KRAS G12C Inhibitor: Synthesis and Structure–activity Relationships of 1-{2,7-diazaspiro[3.5]non-2-yl}prop-2-en-1-one Derivatives As Covalent Inhibitors with Good Potency and Oral Activity for the Treatment of Solid Tumors

Tomoyoshi Imaizumi,Itsuro Shimada, Yuki Satake, Shohei Yamaki,Takanori Koike,Takahiro Nigawara,Osamu Kaneko,Y. Amano,Kenichi Mori,Yosuke Yamanaka,Ayako Nakayama,Yoshihiro Nishizono,Masashi Shimazaki, Takahiro Nagashima,Kazuyuki Kuramoto

Bioorganic & Medicinal Chemistry（2023）

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Abstract LB246: Enfortumab Vedotin, a Nectin-4-directed Antibody-Drug Conjugate, Demonstrates Compelling Antitumor Activity in Non-Muscle Invasive Bladder Cancer Models Which Predicts Minimal Systemic Exposure when Administered by Intravesical Instillation in Patients

Devra Olson,Yen Lin Chia, Enaharo Iboi,Lauren Farr, Maddy Burcher,Anthony Lee,Kelly Hensley,Sean Allred,Abbie Wong,Masashi Shimazaki,Masamichi Mori,Sharsti Sandall,Christopher Carosino

CANCER RESEARCHno. 8 (2023)

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ASP2138, a Novel 2+1 Format, Claudin 18.2 X CD3 Bispecific Antibody, Demonstrates Selectivity and Activity in Preclinical Cancer Models

Taisuke Nakazawa,Hiroaki Tanaka,Aya Kikuchi,Rumana Rashid,Kendra N. Avery,Jing Qi,Alex Nisthal,Masashi Shimazaki,Kenna Shirasuna

CANCER RESEARCH（2023）

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Abstract A173: ASP2074, a Novel Tetraspanin 8 X CD3 Bispecific Antibody, Demonstrates Selectivity and Antitumor Activity in Preclinical Cancer Models

Yoshiyuki Tenda, Yuichi Hanada,Hiroaki Tanaka,Masashi Shimazaki,Kenna Shirasuna

Molecular Cancer Therapeuticsno. 12_Supplement (2023)

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Discovery of ASP6918, a KRAS G12C Inhibitor: Synthesis and Structure-Activity Relationships of 1-{2,7-diazaspiro[3.5]non-2-yl} Prop-2-en-1-one Derivatives As Covalent Inhibitors with Good Potency and Oral Activity for the Treatment of Solid Tumors

Tomoyoshi Imaizumi,Itsuro Shimada,Yoshiki Satake,Susumu Yamaki,Takanori Koike,Takahiro Nigawara,Osamu Kaneko,Yasushi Amano,Kenichi Mori,Yosuke Yamanaka,Ayako Nakayama,Yoshihiro Nishizono,Masashi Shimazaki,Takeyuki Nagashima,Kazuyuki Kuramoto

Bioorganic & medicinal chemistry（2023）

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ASP2074, a Novel Tetraspanin 8 X CD3 Bispecific Antibody, Demonstrates Selectivity and Antitumor Activity in Preclinical Cancer Models

Yoshiyuki Tenda, Yuichi Hanada,Hiroaki Tanaka,Masashi Shimazaki,Kenna Shirasuna

MOLECULAR CANCER THERAPEUTICSno. 12 (2023)

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Discovery and Biological Evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one Derivatives As Covalent Inhibitors of KRAS G12C with Favorable Metabolic Stability and Anti-Tumor Activity

Tomoyoshi Imaizumi,Michinori Akaiwa, Tomoaki Abe,Takahiro Nigawara,Takanori Koike,Yoshiki Satake,Kazushi Watanabe, O. Kaneko, Y. Amano, K. Mori, Y. Yamanaka,Takeyuki Nagashima,Masashi Shimazaki,Kazuyuki Kuramoto

Bioorganic & Medicinal Chemistry (2022)

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Discovery and Biological Evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one Derivatives As Covalent Inhibitors of KRAS G12C with Favorable Metabolic Stability and Anti-Tumor Activity

Tomoyoshi Imaizumi,Michinori Akaiwa, Tomoaki Abe,Takahiro Nigawara,Takanori Koike,Yoshiki Satake,Kazushi Watanabe,Osamu Kaneko,Yasushi Amano,Kenichi Mori,Yosuke Yamanaka,Takeyuki Nagashima,Masashi Shimazaki,Kazuyuki Kuramoto

Bioorganic & medicinal chemistry（2022）

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Enfortumab Vedotin, a Nectin-4 Directed ADC, Demonstrates Compelling Tolerability and Anti-Tumor Activity with Intravesical Instillation in Preclinical Models of Non-Muscle Invasive Bladder Cancer

Christopher Carosino,Devra Olson,Katie Snead,Anthony Lee,Lauren Farr, Amit Garg,Christine O'Day,Esther Trueblood, Jennifer Wright,Mark Bieda, Charles Caldwell,Kelly Hensley,Sean Allred,Bernard Liu,Masashi Shimazaki,Sharsti Sandall

CANCER RESEARCHno. 12 (2022)

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