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In parallel with his clinical career Dr. Slepian has had an extensive research career leading to the development of innovative diagnostics and therapeutics for cardiovascular diseases. His work has focused on the development and use of novel biomaterials for tissue engineering, drug delivery and medical device development. His lab has developed many novel diagnostics and therapeutics which have found their way into clinical use today including: drug-eluting stent technologies, stent coatings, “polymer paving,” surgical anti-adhesive barriers, stretchable and biodegradable electronics, synthetic tissue sealants, myocardial revascularization and cell delivery methods and cardiovascular prosthetic devices - including the total artificial heart. Dr. Slepian’s lab has also, for years, been heavily involved in basic science concentrating on three main areas: 1. the role of cell-matrix interactions in vascular disease, 2. basic aspects of cell-material interactions and 3. the impact of physical forces (notably shear and sound) on platelet activation.
研究兴趣
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Journal of the American College of Cardiologyno. 13 (2024): 445
biorxiv(2024)
Elsevier eBooks (2023)
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Artificial Organsno. 6 (2023): 971-981
Asaio Journalno. Supplement 2 (2023): 62-62
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Asaio Journalno. Supplement 2 (2023): 157-157
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Journal of diabetes science and technologypp.19322968231190413-19322968231190413, (2023)
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