基本信息
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Bio
The aim of my research is to understand the molecular mechanisms that govern how cells maintain the quality of proteins during cellular stress, towards developing novel strategies for therapeutic intervention in cancer and neurodegenerative diseases.
Of particular interest, we seek to gain structural and mechanistic insights into how the Unfolded Protein Response, a key cell signaling system that maintains protein homeostasis within the ER, is activated and how the signal is subsequently propagated.
We utilize a multidisciplinary approach that encompasses structural biology, biochemistry, and cellular techniques, to characterize proteins and complexes involved in ER stress pathways.
Of particular interest, we seek to gain structural and mechanistic insights into how the Unfolded Protein Response, a key cell signaling system that maintains protein homeostasis within the ER, is activated and how the signal is subsequently propagated.
We utilize a multidisciplinary approach that encompasses structural biology, biochemistry, and cellular techniques, to characterize proteins and complexes involved in ER stress pathways.
Research Interests
Papers共 30 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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引用量
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期刊级别
合作者
合作机构
FRONTIERS IN MOLECULAR BIOSCIENCES (2023)
medRxiv (Cold Spring Harbor Laboratory) (2023)
Rodrigo Fernández-Gajardo, Hery Urra,Mauricio Saéz,Philippe Pihán,Beatriz Fonseca, Carolina Sanchez-Doñas,Maruf M. U. Ali,Sarah L. Rouse,Gabriel Cavada, Claudia Tissera, Rómulo Melo,David Rojas,
medrxiv(2023)
Cancer Research (2019): 1775-1775
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Author Statistics
#Papers: 29
#Citation: 3318
H-Index: 16
G-Index: 21
Sociability: 5
Diversity: 2
Activity: 5
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