基本信息
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Bio
The research of prof Smit focuses on novel concepts of G protein-coupled receptors (GPCRs) (e.g. constitutive activity, endosomal signaling, dimerisation, EV biology) and targeting/understanding of (oncogenic) signaling networks activated by human and viral chemokine receptors. This division has ample experience in drug discovery aspects of GPCRs and collaborate with leading pharmaceutical/biotech companies, resulting in several patents. In the last decade Smit has identified several nanobodies (llama-derived antibodies) targeting and modulating human and viral chemokine receptor function.
Research Interests
Papers共 308 篇Author StatisticsCo-AuthorSimilar Experts
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Nature communicationsno. 1 (2024): 4611-4611
Aurelien M. Zarca, Ilze Adlere, Cristina P. Viciano, Marta Arimont-Segura,Max Meyrath,Icaro A. Simon,Jan Paul Bebelman, Dennis Laan,Hans G. J. Custers,Elwin Janssen, Kobus L. Versteegh, Maurice C. M. L. Buzink,
MOLECULAR PHARMACOLOGYno. 4 (2024): 301-312
Lotte Di Niro, Amber C. Linders, Thomas Glynn,D. Michiel Pegtel,Marco Siderius,Caitrin Crudden,Martine J. Smit
Extracellular Vesicles and Circulating Nucleic Acidsno. 2 (2024): 233-48
biorxiv(2023)
Fjodor Bekedam,Marisa Smit,Rowan Smal,Anton Vonk Noordegraaf,Harm J. Bogaard,Marie J. Goumans, Frances S. De,Aida Llucia-Valldeperas
Science Signalingno. 798 (2023)
CANCER RESEARCHno. 7 (2023)
EUROPEAN RESPIRATORY JOURNAL (2023)
crossref(2023)
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