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个人简介
My career focus has been the application of molecular genetics to the understanding and treatment of disease. I have studied genes involved in leukaemia, Mendelian disease, and many complex traits. Much of my work has explored the impact of genetic variability on drug responses, including use of next generation and genome sequencing methods, and gene expression analysis of drug effects in animal and cellular models. I have also contributed to the understanding of complex human traits and diseases including inflammatory bowel disease, addiction, depression, and eating disorders. Additional research themes include G-quadruplex DNA structures and their relevance to imprinting and other aspects of genome biology, and the epigenomics of drug responses and disease.
研究兴趣
论文共 274 篇作者统计合作学者相似作者
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Nora I. Strom, Brad Verhulst, Silviu-Alin Bacanu,Rosa Cheesman,Kirstin L. Purves, Hüseyin Gedik,Brittany L. Mitchell,Alex S. Kwong,Annika B. Faucon,Kritika Singh, Sarah Medland,Lucia Colodro-Conde,
medrxiv(2024)
crossref(2024)
Melanie B Morillon, Alexander Nørup,Jasvinder A Singh,Nicola Dalbeth,William J Taylor,Martin A Kennedy, Birthe Mette Pedersen,Rebecca Grainger,Peter Tugwell,Fernando Perez-Ruiz,Cesar Diaz-Torne,N Lawrence Edwards,
Frontiers in Pharmacology (2023): 1080117
Clinical pharmacology and therapeuticsno. 6 (2023): 1220-1237
Journal of Eating Disordersno. 1 (2022): 1-13
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