基本信息
浏览量:15
职业迁徙
个人简介
Dr. Mark Groudine studies how cells turn genes on and off, and how changes to these processes can lead to cancer. He has shown that the packaging and 3D organization of DNA changes by type of tissue, and that this influences gene expression. Dr. Groudine’s work led to the discovery of a region of DNA that helps to control the expression of hemoglobin, the oxygen-transporting protein in red blood cells. A specific type of anemia, called thalassemia, occurs when this region of DNA is missing. Similar DNA regions have been discovered for other genes and have been implicated in other diseases, including a type of lymphoma.
研究兴趣
论文共 295 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Amy R Strom,Ronald J Biggs,Edward J Banigan,Xiaotao Wang,Katherine Chiu, Cameron Herman, Jimena Collado,Feng Yue,Joan C Ritland Politz,Leah J Tait,David Scalzo,Agnes Telling,
crossref(2021)
Steven J. Collins,Mark T. Groudine
Gene Amplification in Mammalian Cellspp.397-404, (2020)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn