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My lab studies individuals with epilepsy, focussing on one broad question: why do epileptic seizures start? In collaboration with mathematicians and engineers, we construct models of the human brain using a range of imaging and neurophysiological techniques, such as functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), electroencephalography (EEG), simultaneous EEG-fMRI and simultaneous transcranial magnetic stimulation (TMS)-EEG. We aim to understand the underlying mechanisms of seizure onset in terms of such models, comparing healthy people with people who have epilepsy. We also examine how antiepileptic drugs alter brain networks. In addition, we are investigating the long timescale mechanisms of epilepsy, through longterm monitoring of physiological parameters in people with epilepsy, using wearable and implantable sensors. We will use these data to understand why seizures occur at particular times and to forecast seizure onset in real-time.
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Papers共 356 篇Author StatisticsCo-AuthorSimilar Experts
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Daniel Peterson, Mark Van Poppel,Warren Boling, Perry Santos,Jason Schwalb,Howard Eisenberg,Ashesh Mehta,Heather Spader,James Botros, Frank D. Vrionis,Andrew Ko,P. David Adelson,
bioRxiv : the preprint server for biology (2024)
Scientific reportsno. 1 (2024): 15823-15823
bioRxiv the preprint server for biology (2024)
EPILEPSY & BEHAVIOR (2024): 109609-109609
bioRxiv : the preprint server for biology (2024)
V. Santoro, M.D. Hou,I. Premoli,P. Belardinelli, A. Biondi, A. Carobin, F. Puledda,P.G. Michalopoulou,M.P. Richardson,L. Rocchi,S.S. Shergill
Brain Research Bulletin (2024): 110972-110972
Frontiers in human neuroscience (2024): 1383714-1383714
Epilepsiano. 4 (2024): 1017-1028
ISCIENCEno. 6 (2024): 110003-110003
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