Mark leads a vibrant team conducting research on biopsychosocial determinants of pain, response to electrophysical agents, epidemiology of pain, psychophysiological dis-ease, perceptual embodiment, and health promotion. Current projects include pain education, community pain services, artist-led activities for pain, and painogenicity (pain through a socio-ecological evolutionary mismatch lens).

Mark is a world expert on transcutaneous electrical nerve stimulation (TENS) and in 2023 published the largest meta-analysis on TENS to date. He has expertise in quantitative and qualitative methodologies and in conducting clinical trials (phase 1-3), laboratory studies on humans, and evidence syntheses (meta-analyses, meta-ethnography and Cochrane reviews). He has attained over £2 million in research income, and undertakes expert consultancy on behalf of the university for the public and private sectors.