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个人简介
Dr. Mark Brockman received his PhD in Virology from Harvard University in 2001. He completed postdoctoral training at Harvard Medical School (with David Knipe) and the Massachusetts General Hospital (with Bruce Walker). In 2007, he was appointed as Instructor in Medicine at Harvard Medical School. Dr. Brockman arrived at Simon Fraser University (Canada) in September 2009 as Associate Professor in the Department of Molecular Biology and Biochemistry, and he joined the Faculty of Health Sciences in September 2011 as a Canada Research Chair (Tier 2) in Viral Pathogenesis and Immunity.
Research Interests: Dr. Brockman uses molecular and cell biology approaches to investigate questions at the interface of virology, pathogenesis, and the host immune response to human immunodeficiency virus (HIV). His laboratory has developed in vitro methods to examine HIV protein function and host T cell activity, allowing unique population-level analyses of this epidemic that may assist in the development of a vaccine against HIV/AIDS. Strong international collaborations with investigators in Africa and elsewhere are being used to examine global host and HIV diversity. Current studies focus on understanding the impact of HIV immune escape mutations on cytotoxic T lymphocyte (CTL) recognition and on viral protein function; measuring the ability of T cell receptors (TCR) to recognize HIV-infected cell targets; and developing immune-mediated approaches to eradicate latent HIV infection.
研究兴趣
论文共 233 篇作者统计合作学者相似作者
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VACCINESno. 5 (2024): 447
Nelson Sonela,Jaclyn Mann,Celestin Godwe, Oumarou H Goni, Mérime Tchakoute, Nathalie Nkoue,Tulio de Oliveira,Mark A Brockman,Zabrina L Brumme,Thumbi Ndung'u,Marcel Tongo
Frontiers in virology (Lausanne, Switzerland) (2024)
AIDSno. 12 (2023): F25-F35
Open forum infectious diseasesno. 3 (2023)
Journal of Immunologyno. 1 (2023): 75.49-75.49
crossref(2023)
C. Beelen,P. Cheung,W. Dong, N. Bacani,P. Sereda, H. Lapointe,A. Le,R. Barrios, R. Plank, E. Asante-Appiah, R. E. Campo,J. S. Montaner,
HIV MEDICINE (2023): 357-358
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