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个人简介
I, the undersigned Mariana Carmen Chifiriuc (maiden name Balotescu) started my research career in 1997, as a microbiologist in the National Institute for Research and Development in Microbiology and Immunology “I. Cantacuzino” of Bucharest, in the National Reference Center for Vibrio and my universitary career in 2003, at the University of Bucharest (UB), Faculty of Biology, as a Lecturer at the Department of Botany and Microbiology, where, since 2007, I am Associate Professor.
I am teaching courses (General microbiology, Medical microbiology, Medical bacteriology, Standardization of the microbiological control of water, food, air and pharmaceutical products) and practical works (Immunobiology, Clinical immunology and serology, General and applied microbiology, Virology) for undergraduated, Master, PhD and Posdoctoral students. Since 2006, as scientific advisor of CALILAB (Association for quality in laboratories) (http://www.calilab.ro/), I am invited for annual training courses of clinical bacteriology for specialists working in the sanitary system in Romania, being also implicated in the design and validation of the external quality control schemes results for microbiology.
After delivering my PhD in 2005, I have started to apply for funding independently, winning as project manager 5 national projects (CEEX 1460/2006, CNCSIS 187/2007, IDEAS 296/2007, HUMAN RESOURCES 76/2010, IDEAS 154/2011), all of them approaching new areas for Romanian research and I participated as a team member in other 31 research grants, out of which 4 international (FP7-http://www.rower-eu.eu:8080/rower/, COST B23, Phare - national expert, EARSS-European Antimicrobial Resistance Surveillance System - National Data Manager for Romania -http://www.ecdc.europa.eu/en/activities/surveillance/EARS-Net/).
The main research directions approached in my projects and illustrated by the resulting publications are: i) complex phenotypic and genotypic investigation of antibiotic resistance (AR) and virulence markers, as well as of their regulators (quorum sensing system) in clinical and environmental strains; ii) investigation of host-pathogen crosstalk during the infectious process (virulence genes expression, cytokine profiles, apoptosis markers, heat shock proteins and their specific antibodies); iii) assessment of the microbicidal/microbiostatic/anti-pathogenic (qorum-sensing inhibitory) activity of newly synthesized chemical substances, probiotics and vegetal extracts and optimizing the in vitro and in vivo methodology for their selection; v) investigation of the interaction of hybrid nanomaterials with planktonic and adherent microbial cells.
I am the main author/co-author of 12 books, 4 of them monographs (2 published by the Romanian Academy Publishing House- Antibiotics and antimicrobial chemotherapeutic substances; Toxins and other potentially toxic substances), 10 patents (probiotic strains, original experimental models for the investigation of microbial biofilms susceptibility, new antimicrobial substances), published >200 papers (88 in ISI journals with >600 ISI citations, Hirsh index 11 for), I participated with > 160 oral communications/posters in different scientific events. I was coordinator or member in the scientific/organizing committee of 4 international workshops and 3 conferences. I was invited as plenary speaker in 6 international conferences and workshops. I am member in the Editorial Board of 3 Romanian journals indexed in international databases: i) Roum Arch. Immunol. Microbiol. (http://www.roami.ro/index.ph p?q=board); ii) Biointerface Research in Applied Chemistry (http://biointerfaceresearch.com/editorial-board/);iii)BioNanoLetters (http://nanobioletters.com/). I have been recently invited as Guest editor for a special issue in Current Organic Chemistry (impact factor 2.9; SRI 2) with the Topic: Quorum sensing inhibitors: synthesis, optimization, and emerging biomedical applications (http://benthamscience.com/coc/HT/Carmen.pdf). I received 2 national prizes for posters presented in different scientific events. I am reviewer of at least 10 ISI or IDB indexed journals, as well as Ideas projects evaluator.
研究兴趣
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024): 116268-116268
FRONTIERS IN IMMUNOLOGY (2024): 1273604-1273604
Ioana C. Marinas,Leonard Ignat,Ignat E. Maurusa, Madalina D. Gaboreanu,Coroaba Adina,Marcela Popa,Mariana C. Chifiriuc,Marian Angheloiu,Mihaela Georgescu,Alexandra Iacobescu,Gratiela Gradisteanu Pircalabioru,Miruna Stan,
HELIYONno. 4 (2024): e26047-e26047
Adelina-Gabriela Niculescu,Mihaela Georgescu,Ioana Cristina Marinas,Cem Bulent Ustundag, Gloria Bertesteanu,Mariana Pinteală,Stelian Sergiu Maier, Cristina Maria Al-Matarneh,Marian Angheloiu,Mariana Carmen Chifiriuc
Current treatment options in oncologyno. 1 (2024): 97-126
CERAMICS INTERNATIONALno. 1 (2024): 1742-1755
Marian Constantin,Mariana Carmen Chifiriuc,Grigore Mihaescu,Nicolae Corcionivoschi,Liliana Burlibasa,Coralia Bleotu,Sorin Tudorache, Magda Mihaela Mitache,Roxana Filip, Simona-Gloria Munteanu,Gratiela Gradisteanu Pircalabioru
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 3 (2023)
Pharmaceuticsno. 5 (2023): 1458-1458
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